657彩票网 北京pk10

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中醫藥大全 > 藥材 > 中藥材 > D > 地龍

地龍

2017-06-14 11:46 作者:老中醫 閱讀:

《中國藥典》:地龍

【YAOCAIMINGCHENG】DILONG

【PINYIN】Dì Lónɡ

【YINGWENMING】PHERETIMA

657彩票网 北京pk10 【BIEMING】QIUYIN、QUSHAN、QUCHONG、TUSHAN、CHICHONG

【來源】本品為巨蚓科動物參環毛蚓Pheretima aspergillum (E. Perrier)、通俗環毛蚓Pheretima vulgaris Chen、威廉環毛蚓Pheretima guillelmi (Michaelsen)或櫛盲環毛蚓Pheretima pectinifera Michaelsen 的干燥體657彩票网 北京pk10。前一種習稱“廣地龍”,后三種習稱“滬地龍”。廣地龍春季至秋季捕捉,滬地龍夏季捕捉,及時剖開腹部,除去內臟及泥沙,洗凈,曬干或低溫干燥。

657彩票网 北京pk10 【XINGZHUANG】GUANGDILONG:CHENGCHANGTIAOZHUANGBOPIAN,WANQU,BIANYUANLVEJUAN,CHANG15~20cm,KUAN1~2cm。QUANTIJUHUANJIE,BEIBUZONGHESEZHIZIHUISE,FUBUQIANHUANGZONGSE;DI14~16HUANJIEWEISHENGZHIDAI,XICHENG“BAIJING”,JIAOGUANGLIANG。TIQIANDUANSHAOJIAN,WEIDUANDUNYUAN,GANGMAOQUANCUCAOERYING,SESHAOQIAN。XIONGSHENGZHIKONGZAIDI18JIEFUCEGANGMAOQUANYIXIAOKONGTUSHANG,WAIYUANYOUSHUHUANRAODEQIANPIZHE,NEICEGANGMAOQUANLONGQI,QIANMIANLIANGBIANYOUHENGPAI(YIPAIHUOERPAI)XIAORUTU,MEIBIAN10~20GEBUDENG。SHOUJINGNANGKONG2DUI,WEIYU7/8ZHI8/9HUANJIEJIANYITUOYUANXINGTUQISHANG,YUEZHANJIEZHOU5/11。TIQING,LVECHENGGEZHI,BUYIZHEDUAN。QIXING,WEIWEIXIAN。

HUDILONGCHANG8~15cm,KUAN0.5~1.5cm。QUANTIJUHUANJIE,BEIBUZONGHESEZHIHUANGHESE,FUBUQIANHUANGZONGSE;SHOUJINGNANGKONG3DUI,ZAI6/7ZHI8/9HUANJIEJIAN。DI14~16HUANJIEWEISHENGZHIDAI,JIAOGUANGLIANG。DI18HUANJIEYOUYIDUIXIONGSHENGZHIKONG。TONGSUHUANMAOYINDEXIONGJIAOPEIQIANGNENGQUANBUFANCHU,CHENGHUACAIZHUANGHUOYINJINGZHUANG;WEILIANHUANMAOYINDEXIONGJIAOPEIQIANGKONGCHENGZONGXIANGLIEFENGZHUANG;ZHIMANGHUANMAOYINDEXIONGSHENGZHIKONGNEICEYOU1HUODUOGEXIAORUTU。

657彩票网 北京pk10 【PAOZHI】CHUQUZAZHI,XIJING,QIEDUAN,GANZAO。

657彩票网 北京pk10 【XINGWEI】XIAN,HAN。

【GUIJING】GUIGAN、PI、BANGGUANGJING。

657彩票网 北京pk10 【GONGNENGZHUZHI】QINGREDINGJING,TONGLUO,PINGCHUAN,LINIAO。YONGYUGAORESHENHUN,JINGXIANCHOUCHU,GUANJIEBITONG,ZHITIMAMU,BANSHENBUSUI,FEIRECHUANKE,NIAOSHAOSHUIZHONG,GAOXUEYA。

【YONGFAYONGLIANG】4.5~9g。

657彩票网 北京pk10 【ZHUZANG】ZHITONGFENGGANZAOCHU,FANGMEI,FANGZHU。

【ZHAILU】《ZHONGGUOYAODIAN》

中藥材地龍的圖片
地龍圖片

《中華本草》:地龍

657彩票网 北京pk10 【YAOCAIMINGCHENG】DILONG

【PINYIN】Dì Lónɡ

【BIEMING】QIUYIN、QIN、YIN、QIUYIN、WANSHAN、YINWU、FUYIN、HANYIN、QUSHAN、QUSHAN、TULONG、DILONGZI、TUSHAN、CHONGSHAN

【LAIYUAN】YAOCAIJIYUAN:WEIJUYINKEDONGWUCANHUANMAOYINHEWEILIANHUANMAOYIN、TONGGUHUANMAOYIN、ZHIMANGHUANMAOYINDENGDEQUANTI。QIANYIZHONGYAOCAIXICHENG“GUANGDILONG”,HOUSANZHONGYAOCAIXICHENG“HUDILONG”。

LADINGZHIWUDONGWUKUANGWUMING:1.Pheretima aspergillum(E.Perrier)2.Pheretima guillelmi(Michaelsen)3.Pheretima vulgaris Clen 4.Pheretima pectinifera Michaelsen

CAISHOUHECHUZANG:CHUNJIZHIQIUJIBUZHUO。XIQUZHANYE,JISHIPOUKAIFUBU,XIQUNEIZANGJINISHA,SHAIGANHUODIWENGANZAO。

【YUANXINGTAI】1.CANHUANMAOYIN,TIJIAODA,CHANG110-380mm,KUAN5-12mm。TIBEIBUHUIZISE,FUMIANSHAODAN。QIANDUANJIAOJIAN,HOUDUANJIAOYUAN,CHANGYUANZHUXING。TOUBUTUIHUA,KOUWEIZAITIQIANDUAN。QUANTIYOU100DUOGETIJIEZUCHENG。MEIJIEYOUYIHUANGANGMAO,GANGMAOQUANSHAOBAI。DI14-16JIEJIEGOUTESHU,XINGCHENGHUANDAI,WUGANGMAO。CIXINGSHENGZHIKONG1GEWEIYUDI14JIEFUMIANZHENGZHONG,XIONGXINGSHENGZHIYE1DUIWEIYUDI18JIEFUMIANLIANGCE,SHOUJINGNANGKONG3DUIWEIYU6-7,7-8,8-9JIEJIAN。 2.WEILIANHUANMAOYIN,TICHANG96-150mm,KUAN5-8mm。BEIMIANQINGHUANGSEHUOHUIQINGSE,BEIZHONGQIANSHENQINGSE。HUANDAIZHAN14-16SANJIE,WUGANGMAO。SHENTISHANGGANGMAOJIAOXI,QIANDUANFUMIANBINGBUCUERSHU。XIONGSHENGZHIKONGZAI18JIELIANGCEYIQIANJIAOPEIQIANGNEI,XIANRUSHICHENGZONGLIEFENG,NEIBIYOUZHEZHOU,ZHEZHOUJIANYOUGANGMAO2-3TIAO,ZAIQIANGDITUQISHANGWEIXIONGKONG,TUQIQIANMIANTONGCHANGYOUKONGTOUTU。SHOUJINGNANGKONG3DUI,ZAI6-7,7-8,8-9JIEJIAN,KONGZAIYIHENGLIEZHONGDEXIAOTUQISHANG,WUSHOUJINGNANGQIANG。8-9,9-10JIEJIANQUEGEMO,MANGCHANGJIANDAN。SHOUJINGNANGDEMANGGUANNEIDUAN2/3ZAIPINGMIANSHANG,ZUOYOUWANQU,WEINAJINGNANG。 3.TONGSUHUANMAOYIN,BENZHONGSHENTIDAXIAO、SEZEJINEIBUGOUZAOYUWEILIANHUANMAOYINXIANGSI。WEISHOUJINGNANGQIANGJIAOSHENGUANG,QIANHOUYUANJUNLONGZHONG,WAIMIANKEJIANQIANGNEIDAXIAORUTUGEYI。XIONGJIAOPEIQIANGYISHENGUANG,NEIBIDUOZHOUWEN,YOUPINGDINGRUTU3GE,WEIZHIZAIQIANGDI,YOUYITUWEIXIONGKONGSUOZAICHU,NENGQUANBUFANCHU,YIRUYINJING。

4.ZHIMANGHUANMAOYIN,TICHANG100-150mm,KUAN5-9mm。BEIMIANJICEMIANYOUSHENZISEHUOZIHONGSE。GANGMAOQUANBUBAI,HUANDAIZHAN3JIE,WUGANGMAO。SHENTIQIANBUGANGMAOSUICU,DANZAI2-9JIEBINGBUTESHUCU。XIONGSHENGZHIKONGZAIYIGESHIZIXINGTUDEZHONGYANG,CHANGYOUYIQIANNANGZHUANGPIZHEGAIZHU,NEICEYOUYIGEHUODUOGERUTOU,QIPAILIEBIANHUAHENDA。SHOUJINGNANGKONG3DUI,WEIYU6-7,7-8,8-9JIEJIAN,QIWEIZHIJIJINJIEZHOUDEYIBANJULI,KONGZAIYIRUTOUDEHOUCE,QIANHOULIANGCEBIAOPIXIANZHONGDA,KONGCHANGXIANRU,KONGDENEICEFUMIANZAIGANGMAOQUANQIANHUOHOU,YOURUTOUTU,PAILIEJIAOGUIZE。8-9,9-10JIEJIANQUEGEMO。MANGCHANGFUSHI,QIFUCEYOUZHIZHUANGXIAONANG。FUXINGXIANYOUSUOZHUANGDUANGUAN。MANGGUANJIAOSHOUJINGNANGBENTICHANG,NEIDUAN3/4SHAOCU,HUOZHIHUOSHAOWANQU。

地龍的生態環境:
1.生于潮濕、疏松之泥土中,行運遲緩。
2.生活于潮濕多有機物處。
3.生活于潮濕多有機物處。
657彩票网 北京pk10 4.生活于潮濕多有機物處。

地龍的資源分布:
1.分布于福建、廣東、廣西等地。
2.分布于江蘇、浙江、湖北及上海、天津等地。
3.分布于江蘇、浙江、湖北及上海、天津等地。
657彩票网 北京pk10 4.分布于江蘇南部、浙江及上海、南昌等地。

【ZAIPEI】SHENGHUOXIXING QIUYINWEIYEXINGXINGDONGWU,YIBANQIXIZAICHAOSHIDENIGUIZHONG,SHENDU10-20cm。QIUYINXISHISHI,XIANJING,PAGUANG,PAYAN,PADANNINGWEI。ZAISHENGNENGLIJIAOQIANG,DANGSHOUSHANGBEIQIEDUANZHIHOU,NENGGOUSHENGCHUXINDEZUZHIDAITIDIUSHIDEBUFEN,DANGQIWENDIYU5℃SHI,ZHANRUTUZHONGDONGMIAN。ZASHIXING,SHIXINGGUANGFAN,FANWUDUDEGEZHONGZHIWUJINGXIE、JIACHUFENBIANJIYOUJILAJIDENGJUNKEZUOSILIAOYONG。QIUYINWEICIXIONGTONGTIDONGWU,YITIJIAOPEI,JIAOPEIHOUYUE1XINGQICHANLUAN,CHANLUANYUJIANNEI,MEIJIANNEIHANSHOUJINGLUAN3-4GE,JING2GEYUEZUOYOUFUCHUYOUYIN。 YANGZHIJISHU YANGZHIQIUYINYAOQIUTIAOJIANBUGAO,FANGFADUOYANG。SIYANGTUKEYONGFAJIAOFUSHUDEYOUJIFEIWUHECAIYUANTUDENGHUNHEERCHENG。YAOQIUHANSHUILIANGZAI30%ZUOYOU,pHYI6.8-7.6WEIYI。SIWEIDEYOUJIFEIWURUZUOWUDEJIEGAN、LUOXIE、CHUQINFENBIANDENGXUJINGGUOFAJIAOCHULIHOU,CAINENGBEIQIUYINLIYONG。YANGZHIMIDUBUKEGUODA,WENDUYI21-25℃WEIZUISHICHANLUANWENDU。 SIYANGGUANLI SIYANG2-3GEYUEHOU,YAOYONGKUANGSHAIFA、ERYOUFA、GUAFENFADENGJIANGYINFEN、YINJIANJIYINTIFENKAI。

657彩票网 北京pk10 【XINGZHUANG】XINGZHUANGJIANBIE (1)GUANGDILONG,CHENGCHANGTIAOZHUANGBOPIAN,WANQU,BIANYUANLVEJUAN,CHANG15-20cm,KUAN1-2cm。QUANTIJUHUANJIE,BEIBUZONGHESEZHIZIHUISE,FUBUQIANHUANGZONGSE;DI14-16HUANJIEWEISHENGZHIDAI,XICHENG“BAIJING”,JIAOGUANGLIANG。TIQIANDUANSHAOJIAN,WEIDUANDUNYUAN,GANGMAOQUANCUCAOERYING,SESHAOQIAN。XIONGSHENGZHIKONGZAIDI18JIEFUCEGANGMAOQUANYIXIAOKONGTUSHANG,WAIYUANYOUSHUQUANHUANRAODEQIANPIZHE,NEICEGANGMAOQUANLONGQI,QIANMIANLIANGBIANYOUHENGPAI(YIPAIHUOERPAI)XIAORUTU,MEIBIAN10-20GEBUDENG。SHOUJINGNANGKONG3DUI,WEIYU6-9JIEJIANYITUOYUANXINGTUQISHANG,YUEZHANJIEZHOU5/11。TIQING,LVECHENGGEZHI,BUYIZHEDUAN。QIXING,WEIWEIXIAN。(2)HUDILONG,CHANG8-15cm,KUAN 0.5-1.5cm。QUANTIJUHUANJIE,BEIBUZONGHESEZHIHUANGHESE,FUBUQIANHUANGZONGSE;SHOUJINGNANGKONG3DUI,ZAI6-7,7-8,8-9JIEJIAN。DI14-16JIEWEISHENGZHIDAI,JIAOGUANGLIANG。DI18JIEYOU1DUIXIONGSHENGZHIKONG。TONGGUHUANMAOYINDEXIONGJIAOPEIQIANGKONGCHENGZONGXIANGLIEFENGZHUANG;ZHIMANGHUANMAOYINDEXIONGSHENGZHIKONGNEICEYOU1GEHUODUOGEXIAORUTU。 XIANWEIJIANBIE GUANGDILONG(CANHUANMAOYIN)FENMOSHENG:DANHUISEHUOHUIHUANGSE。①XIEWENJIXIANWEIWUSE,SHAOSHUDANZONGSE,JIXIANWEIYISANLIHUOXIANGHUWENJIAOJIE,DADUOWANQUHUOSHAOPINGZHI,ZHIJING4-36(-66)μm,BIANYUANCHANGBUZHENGQI,YOUDEJUBUPENGDA,MINGJIANXIANGJIANWENLIBUMINGXIAN。②BIAOPIHUANGLVHUOHUANGZONGSE,XIBAOJIEXIANBUMINGXIAN,YOUANZONGSESESUKELI,SANZAIHUOJUJICHENGTIAOZHUANG、WANGZHUANG。③GANGMAOSHAOJIAN,CHANGSUIDUANSANZAI,DANZONGSEHUOHUANGZONGSE,ZHONGBUZHIJING34-63μm,XIANDUANDUODUNYUAN,BIAOMIANKEJIANZONGLIEWEN。PINZHIBIAOZHI 《ZHONGHUARENMINGONGHEGUOYAODIAN》1995NIANBANGUIDING:BENPINZHONGJINSHUBUDEGUOBAIWANFENZHISANSHI;JINCHUWUYONGREJINFACEDING,SHUIJINCHUWUBUDESHAOYU16.0%。

657彩票网 北京pk10 【HUAXUECHENGFEN】CANHUANMAOYINHEBEIANYICHUNYINHANRONGXUECHENGFEN:QIUYINSU(lumbritin),JIERECHENGFEN:QIUYINJIEREJIAN(lumbrofebin),YOUDUCHENGFEN:QIUYINDUSU(terrestro-lumbrilysin)DENG。HUANHAN6-QIANJIPIAOLING( hypoxanthine),HUANGPIAOLING(xanthine),XIANPIAOLING(adenine),NIAOPIAOLING(guanine),GUA(guanidine),DANJIAN(choline),YIJIBINGANSUAN(alanine),XIEANSUAN(valine),LIANGANSUAN(leucine),BENBINGANSUAN(phenylalanine),LAOANSUAN(tyrosine),LAIANSUAN(lysine)DENGANJISUAN。WOGUOSHIMIANCHUSHOUDECHIZIAISHENGYINHEMEIGUOHONGYINJIHONGSEAISHENGYINDEZAJIAOZHONG,CHENGWEI“DAPINGERHAOYIN”,QIZHONGHANYOUTIANDONGANSUAN(aspartic acid),SUANSUAN(threonine),SIANSUAN(serine),GUANSUAN(glutamic acid),GANANSUAN(glycine),BINGANSUAN,XIEANSUAN,DANANSUAN(methionine),YILIANGANSUAN(isoleucine),LIANGANSUAN,LAOANSUAN,BENBINGANSUAN,LAIANSUAN,ZUANSUAN(histidine),JINGANSUAN(arginine),FUANSUAN(proline)HEXIN、TONG、TIE、GE、XI、MU、WA、MEIDENGYUANSU。JINNIANCONGCHIZIAIXINGYINTINEIZHAOCHUXUEXIAOBANHUOHUAYINZI(platelet activating factor),QIQIANTIWUZHI1-O-WANJI-2-XIANJI-sn-GANYOU-3-LINSUANDANJIAN(1-O-alkyl-2-acyl-sn-glycerophosphocholine)ZHANLINZHIXIANDANJIAN(phosphatidylcholine)DEBILIGAODA61.4%。

【YAOLIZUOYONG】1.RONGSHUANHEKANGNINGZUOYONG CANHUANMAOYINTIQIANGYEGANCUFENZHIJIEZHURUDASHUSHIERZHICHANG30mg/kg,YIDONGJINGMOCHAGUANCHUANXIANZHANFUXIANWEIDANBAIFANGFACEXIANWEIDANBAISHENGCHENG,JUYOUMINGXIANDERONGXIANWEIDANBAIHUOXING,ZHUFEIHUOHONGGANHOUHUOXINGJISANGSHI。YIXIANWEIDANBAIPINGBANCEDINGFAZHENGMING,DONGGANCUFEN5μgYUNIAOJIMEI1uDERONGXIANWEIDANBAIHUOXINGXIANGDANG。DANXIANWEIDANBAIPINGBANJING85℃SHUIYUJIARE30minHOU,NIAOJIMEIDEHUOXINGSANGSHIERDONGGANCUFENDEHUOXINGRENGBUFENBAOLIU。SHUOMINGDONGGANCUFENRONGXIANWEIDANBAIJIZHIYUNIAOJIMEIBUWANQUANYIYANG。NIAOJIMEIDEZUOYONGSHIJIHUOXIANWEIDANBAIRONGMEIYUANSHIZHICHENGWEIYOUHUOXINGDEXIANRONGYE,CUIHUAXIANWEIDANBAIRONGJIE,QIUYINDONGGANCUFENCHULEYOUNIAOJIMEIYANGXIANRONGZUOYONGWAI,SHANGYOUZHIJIECUIHUAXIANWEIDANBAISHUIJIEDEZUOYONG。CHIZIAISHENGYINTIQUYEZAITIWAIDUITUJINGMOXUESHUANYOURONGJIEZUOYONG,DUIYININGGUDEXIANWEIDANBAIJIAOBANYEYOUYIDINGXIANRONGHUOXING。QIXIANRONGZUOYONGYOUZHIJIEXIANWEIDANBAIRONGJIEHEJIHUOXIANRONGMEIYUANDEJIANJIEZUOYONG,DANYIZHIJIEXIANRONGWEIZHU。JIATUJINGZHUQIUYINSHUIJINYE0.lg/kgHUO0.2g/kg,DUIJINGZONGDONGMOYIJINGWAIJINGMOXUELIUTAOLUFASHIYANXINGXUESHUANXINGCHENGYOUMINGXIANYIZHIZUOYONG,GUANFU1g/kgYIYOUMINGXIANYIZHI,DANRUANRUO,JINGZHU0.02g/kgYOURONGSHUANZUOYONG。JIATUJINGZHUGUANGDILONG(Lumbricus kangtang6nsis)CHUNTIQUZHUSHEYE(MEI 1mlHANSHENGYAO 2g)2ml/kg,KEMINGXIANYANCHANGXUEXIAOBANXUESHUANHEXIANWEIDANBAIXUESHUANXINGCHENGSHIJIAN,SHIXUESHUANCHANGDUHEGANZHONGJIANSHAO,BINGJIANGDIXUEYEZHANDU。JIATUJINGZHURENGONGYANGZHIDEZHENGYINKESHUANGXIONGYINSHU(Lumbricche bimastos)CUTIQUYE,KEXIANZHUJIANGDIXUEZHONGXIANWEIDANBAIYUANHANLIANG,BINGSHIDAIQIUDANBAIRONGJIESHIJIANXIANZHUSUODUAN。CUTIQUYEJINGJINYIBUCUIQU,ZHIBEICHUHANDUOZHONGXIANRONGMEIHEXIANRONGMEIYUANJIHUOWUDEZHIJI,JUYOULIANGHAODERONGJIEXUESHUANZUOYONG,KESHITUXUEJIANGZUZHIXINGXIANRONGMEIYUANJIHUOWU(t-PA)HUOLIZENGJIA,XUEXIAOBANJUJIXINGXIANZHUJIANGDI,QUANXUEZHANDUHEXUEJIANGZHANDUJIANGDI,HONGXIBAOGANGXINGZHISHUJIANGDI,TISHIQITONGGUOCUJINXIANRONG、YIZHIXUEXIAOBANJUJI、ZENGQIANGHONGXIBAOMOWENDINGXINGDENGFAHUIZUOYONG。QIUYINGANFENSHUIJINYEZAITIWAIDUIJIATUXIANWEIDANBAIHENINGXUEKUAIJUNYOURONGJIEZUOYONG。JIATUJINGZHUSHUIJIANCHUNCHENZHUSHEYEDUIERYUANJINGMOXUESHUANYOUMINGXIANRONGJIEZUOYONG。ZHENGCHANGZHIYUANZHEKOUFUQIUYINTIQUWUYIYOUMINGXIANDEKANGNINGHEXIANRONGZUOYONG,QIEYUJILIANGXIANGGUAN。NINGXUEHUOMEISHIJIANMINGXIANYANCHANG,XIANRONGMEIYUANJIHUOWUHUOXINGZENGQIANG,DAIQIUDANBAIRONGJIESHIJIANSUODUANJIXIANWEIDANBAIJIANGJIECHANWUHANLIANGZENGJIA。CONGQIUYINTIQUDEXIANRONGMEI(DONGGANFEN)GEIJIATUGUANWEI,0.05g/(kg·d)HUO 0.1g/(kg·d),LIANXU3d,CONGXINZANGQUXUE,ZAITIWAIXINGCHENGDEXUESHUANCHANGDU、SHIZHONG、GANZHONGJUNJIAODUIZHAOZUMINGXIANJIANSHAO。

657彩票网 北京pk10 DILONGJIANJIZAITIWAIDUINIUNINGXUEMEICUJINRENXUEXIANWEIDANBAIYUANNINGJUYOUMINGXIANKANGNINGXUEMEIZUOYONG。CHIZIAISHENGYINTIQUWUDUININGXUEMEISHIJIAN(TT)YOUMINGXIANYANCHANGZUOYONG,ZAIQUEFAKANGNINGXUEMEI-III(AT-III)DEXUEJIANGZHONGJIARUGAITIQUWUYEKESHITTMINGXIANYANCHANG,DANYANCHANGCHENGDUJIAOXIAO,SHUOMINGZHEZHONGZUOYONGYOUYILAIAT-IIIHEBUYILAIAT-IIIDELIANGGEBUFEN。JIATUJINGZHUDILONGTIQUWU(EE)KEMINGXIANYANCHANGTTQIBANSHUAIQI0.32hZAITIWAIEEYIKEMINGXIANYANCHANGTTHEBAITAOTUHUOHUABUFENNINGXUEHUOMEISHIJIAN(KPTT)。GUANGDILONGSHUIJINYEJIAJIANSHUIJIEHOUZAIYONGYICHUNFENJIFENLI,SUOHUOTIQUWUYIKEMINGXIANYANCHANGKPTTHETT,QIKANGNINGXUEMEIHUOXINGBUNENGBEIAT-IIIKANGTIJIYUJINGDANBAIZHONGHE,BIAOMINGQIHUOXINGBUYILAIYUAT-III GAIHUOXINGCHENGFENBUSHUDUOTANGHUODANBAIZHI,KENENGSHIYIZHONGNAIJIANNAIREDEXIAOTAIHUOHANSHUANGJIANHUAHE,YUSHUIWASU、GANSUDENGKANGNINGWUZHIBUTONG。 GAOXUEZHANDUZONGHEZHENGHEQUEXUEXINGZHONGFENGHUANZHEMEIKOUKOUFUCHIZIAISHENGYINTIQUYE,LIANXU14dWEISANLIAOCHENG,FU1~2LIAOCHENG,HUANZHEDEXUEXIBAOBI、XUECHEN、XUEJIANGZHANDU、XUEXIANWEIDANBAIYUANDENGJUNYOUJIANGDI。JIATUJINGZHUDILONGTIQUYE,KESHIXUEXIAOBANJUJIXINGXIANZHUJIANGDI,QUANXUEZHANDUHEXUEJIANGZHANDUJIANGDI,HONGXIBAOGANGXINGZHISHUJIANGDI。 2.DUIXINXUEGUANXITONGDEZUOYONG (1)KANGXINLVSHICHANGZUOYONGGEIDONGWUJINGZHUDILONGZHUSHEYEDUILVFANGYISHENSHANGXIANSUHUOWUTOUJIANYOUFADEDASHUXINLVSHICHANG,LVHUABEIHUODUMAOHUAZHUGYOUFADEJIATUXINLVSHICHANGJUNYOUMINGXIANDEDUIKANGZUOYONG;DUIXINZANGCHUANDAOYIYOUYIZHIZUOYONG。

(2)JIANGXUEYAZUOYONGMAZUIQUANJINGZHUGUANGDILONGRESHUIJINJIHUOYICHUNJINCHUYE0.1g/kg,30~45minCHUXIANXUEYAXIAJIANG,KEWEICHI2YI3h;ZHENGCHANGDASHUSANCIGUANWEIDAJILIANG(10g/kg)HUOSHENXINGGAOXUEYADASHUMEIRIZHUNWEIXIAOJILIANG(50mg/kg),LIANXU2XINGQI,JUNYOUMINGXIANDEJIANGYAZUOYONG。SHENXINGGAOXUEYADASHUXUEYAXIAJIANGCHUXIANYUGEIYAOHOU3~7dBINGYUTINGYAOHOUDI2XINGQIHUISHENGDAOYONGYAOQIANSHUIPING。GUANGDILONGDEJIANGYAJIZHIKENENGSHIYOUYUTAZHIJIEZUOYONGYUJISUIYISHANGDEZHONGSHUSHENJINGXITONGHUOTONGGUOMOUXIENEIGANSHOUQIFANSHEDIYINGXIANGZHONGSHUSHENJINGXITONG,YINQIBUFENNEIZANGXUEGUANDEKUOZHANGERSHIXUEYAXIAJIANG。DASHUJINGWANGGUANGDILONGJIANJI0.25g/kg,LIJIYINQIXUEYAXIAJIANG,QIJIANGYAGUOCHENGYUXUEXIAOBANHUOHUAYINZI(PAF)XIANGSI,RUYUXIANJINGZHUPAFSHOUTIZUZHIJICV6209XIANZHUYIZHIGUANGDILONGDEJIANGYAZUOYONG,TISHILEIPAFWUZHISHIGUANGDILONGDEZHONGYAOJIANGYACHENGFEN。DUIYIZUZHONGZIFAXINGGAOXUEYADASHU(SHRSP)WEISHIHANDILONGSILIAO,KEZAIBUYINGXIANGSHPSPTIZHONGDEQINGKUANGXIAJIANGDISHRSPXUEYA,GAISHANXUEGUANDANXINGJIZENGJIAZHUDONGMOFUHESHIZHONGBI(LALIg/ZHUDONGMOSHIZHONGmg)HEDUANLIESHIZHUDONGMOZUIDAFUHE(LALIg/ZHUDONGMOSHIZHONGmg),JIANGDIXINTIZHONGBI(XINJImg/TIZHONGg ×10-3),ZENGJIASHENTIZHONGBI,QIEHUANJUYOULINA、LINIAOHEJIANGDISANSUANGANYOUZUOYONG,TISHIDILONGKENENGYOUYIDINGDEYUFANGSHRSPZUZHONGFASHENGDEZUOYONG。

3.DUIZHONGSHUSHENJINGXITONGDEZUOYONG①ZHILIAOQUEXUEXINGNAOZUZHONG(ZHONGFENG):YUXIANFUQIANGZHUSHEDILONGZHUSHEYE10g/kg,DUIMENGGUSHATUSHUYICEYUZONGDONGMOJIEZHAZAOCHENGDEQUEXUEXINGNAOZUZHONGJUYOUYIDINGDEYUFANGZUOYONG,KEJIANQINGQUEXUEXINGNAOZUZHONGDEZHENGZHUANG,RULIMAO、ZHUANQUANXINGWEIHEDAGUNFAZUODENGDEFASHENGLVXIAJIANG,BINGMINGXIANJIANGDIDONGWUDESIWANGLV,SHIQUEXUEXINGNAOZUZHONGDONGWUNAOZUZHIZHONGJIANGDILEDEDANANLEIDIZHI5YIQIANSEANHEDUOBAANQUYUHUIFU,ERDUIQUJIASHENSHANGXIANSUHANLIANGZEWUMINGXIANYINGXIANG。②KANGJINGJUEHEZHENJINGZUOYONG:XIAOSHUFUQIANGZHUSHEDILONGCUSUANQIANCHULIDETIQUYE,KEMINGXIANDUIKANGWUSIDANHEKAFEIYINYINQIDEJINGJUE,DANBUNENGDUIKANGTUDENINGYINQIDEJINGJUE,TISHIQIKANGJINGJUEZUOYONGBUWEISHIZAIJISUIYISHANGDEZHONGSHUSHENJINGBUWEI。XIAOSHUFUQIANGZHUSHEDILONGYICHUNJINCHUYE20g/kg,DUIDIANJINGJUEYEYOUDUIKANGZUOYONG,EDWEI22.18g/kg。DILONGCHUNJINYEDUIXIAOSHU、JIATUYOUZHENJINGZUOYONG。③JIEREZUOYONG:QIUYINSHUIJINJIDUIDACHANGGANJUNNEIDUSUJIWENRECIJIYINQIDEFAREJIATUJUNYOULIANGHAODEJIEREZUOYONG,DANJIAOANJIBILINDEZUOYONGRUO。KOUFUGUANGDILONGSAN 12g,DUIJIANKANGRENTIWENWUJIANGDIZUOYONG,DUIGANRANXINGFAREHUANZHEJIANGWENZUOYONGYOUYUASIPILIN(KOUFU0.3g)DUIFEIGANRANXINGFAREYIYOUXIAO,DANZUOYONGCHUXIANJIAOWAN,YIBANYUFUYUEHOU0.5-3hXIANXIAO,2-5hTIWENJIANGZHIZHENGCHANG。 4.KANGAIZUOYONG XIAOSHUMEIRIGUANFUDILONGTIQUWUl1mg/ZHI,LIANXU58d,DUIYIZHIDEROULIUS180。YOUMINGXIANDEYIZHIZUOYONG,BUJINLIUTIMINGXIANJIANSHAO,QIEKEYANCHANGXIAOSHUDESHENGCUNQI。XIAOSHUMEIRIGUANFUDILONGTIQUWU1mg/ZHI,LIANXU6d,DUIYIZHIXINGSHITILIUH22。YEYOUMINGXIANYIZHIZUOYONG。BANYINTIQUWUJINGTOUXIHOUDETOUXIWAIYEDUIJIEZHONGROULIUS180HUOSHITILIUEMT6。DEXIAOSHUJUNYOUYIZHIZHONGLIUSHENGCHANGDEZUOYONG,GAICHENGFENJING100℃JIARE20min,YIAIZUOYONGJIXIAOSHI。DILONGKETOUXIZUFENZAITIWAIDUIWEIAIXIBAOMGC803DEXIONGXIANMIDINGTUOYANGHEBEI( H3-TdR)DESHENRUYOUMINGXIANYIZHIZUOYONG,GAIZUFENJING56℃JIARE0.5hYILIUZUOYONGRENGRANCUNZAI,BIAOMINGGAIYOUXIAOZUFENFENZIJIAOXIAOERQIENAIRE。YINGYONGNINGJIAOGUOLVJISHUDUIDILONGTIQUWUJINXINGFENLIHUO 4GEZUFEN。ZUFENIZAITIWAIDUIWEIAIXIBAO MGC803DE3H-TdRSHENRUYOUFEICHANGXIANZHUDEYIZHIZUOYONG,GAIZUFENJING56℃JIARE0.5hYILIUZUOYONGRENGCUNZAI,DANJIAOWEIJIAREZUMINGXIANJIANRUO,TISHIGAIZUFENJIAREHOUYILIUZUOYONGBUFENBAOLIU,JUYOUYIDINGNAIREXING。ZUFENIVZAITIWAIDUIWEIAIXIBAOMGC803DE3H-TdRSHENRUYEYOUFEICHANGXIANZHUDEYIZHIZUOYONG,DANGAIZUFENJING56℃JIAWEN0.5hHOUYILIUZUOYONGJIXIAOSHI,TISHIGAIZUFENBUNAIRE,ZUFENIIHEZUFENIIIZEJUNWUYILIUZUOYONG。DILONGTIQUWUZAITIWAIDUIPEIYANGDEHOUAIXIBAO Hep-2YOUNONGDUYILAIXINGYIZHIZUOYONG。XIAOSHUGUANFUDILONGTIQUWUYU5YIFUNIAOHUGUAN(5-FU)LIANHEYINGYONGDUIRUXIANAIMADEZHILIAOYOUMINGXIANXIETONGZUOYONG,ZHONGLIUSHENGCHANGBIDANYONG5-FUYANCHI3d,AIXIBAOBIANXINGHUAISIJIAODANYONGYANZHONG,XIAOSHUCUNHUOSHIJIANYEJIAODANYONGYANCHANGYANGMEN。DILONGTIQUWUYUBAIJIESU2(IL-2)LIANHEYINGYONGDUIXIAOSHUROULIUS180。YIKEYIZHIZHONGLIUSHENGCHANG,BIAOXIANXIETONGZUOYONG。YIZHIROULIUS180。DEXIAOSHUGUANFUDILONGTIQUWU,YU5-FULIANHEYINGYONGSHI,DUIZHONGLIUDEYIZHIYOUXIETONGZUOYONG,RUYUFUSHEZENGXIAOJIAK123LIANHEYINGYONGZECHANSHENGGENGQIANGDEFUSHEZENGXIAOZUOYONG,SANZHEHEYONGZEYILIUXIAOGUOZUIHAO。ZAITIWAI,DILONGTIQUWUYUAK123HEYONGDUIRENHOUAIXIBAOHep-2YEBIAOXIANXIETONGZUOYONG。DILONGTIQUWUYURELIAOLIANHEYINGYONGDUIXIAOSHUSHITILIU EMT6DEYIZHIYEYOUMINGXIANXIETONGZUOYONG。

657彩票网 北京pk10 GUANFUDILONGTIQUWUDUIZHENGCHANGJIHELIU(S180)XIAOSHUJUNYOUCUJINPILINBAXIBAOZHUANHUAZUOYONG,DUIGEIYUZHIXIANDIANZIJIASUQIZHAOSHEHEWEIZHAOSHEXIAOSHUPILINBAXIBAOZHUANHUAYEYOUCUJINZUOYONG;DANTIWAISHIYANZEDUIXIAOSHUPILINBAXIBAOHERENXUELINBAXIBAOZHUANHUAJUNYOUYIZHIZUOYONG。TISHIDILONGTIQUWUKENENGTONGGUOTIGAOJITIMIANYINENGLIERYIZHIZHONGLIUXIBAOSHENGCHANGDE。XIAOSHUFUQIANGZHUSHEDILONGTIQUWU100mg/kg,LIANXU6d,KESHIXIONGXIANJIPIZANGYOUHEXIBAOSHUMINGXIANZENGJIA,PIXIBAODUIDAODOUQIUDANBAIA(ConA)、ZHIDUOTANG(LPS)DEFANYINGXINGJUNMINGXIANGAOYUDUIZHAOZU,PIZANGZIRANSHASHANGXIBAO(NK)JIKANGTIYILAIXIBAOJIEDAOXIBAODU(ADCC)HUOXINGYEXIANZHUGAOYUDUIZHAOZU。DUIHELIUXIAOSHUDEMIANYIGONGNENGYIYOUXIANGSIZUOYONG,DANPIZANGNKJIAfXICHUOXINGZEXIANZHUDIYUDUIZHAOZU。HELIUXIAOSHUJINGSHENBUXXIANZHILIAOJIJUBUZHAOSHEHOU,PIZHONG、PIYOUHEXIBAOSHU、NKXIBAOHUOXING、ADCCHUOXINGJIPAIXIBAOIL-2HUOXINGJUNSHOUDAOYIDINGYIZHI,DANRUJIAYONGDILONGTIQUYEZHILIAO,ZEWEIJIANRENHEMIANYIYIZHIZUOYONG,SHENZHIYOUSUOTIGAO,TISHIDUIJITIMIANYIGONGNENGDOUYOUYIDINGDECUJINZUOYONG。XIAOSHUMEIRIGUANFUDILONGTIQUWU,KESHIWEIXUEZHONGTUNSHIXIBAOHUAXUEFAGUANGZENGQIANG,TISHIKEZENGQIANGTUNSHIGONGNENG;HELIU(S180)XIAOSHUNKXIBAOHUOXINGXIAJIANG,RUGUANFUDILONGTIQUWU8d,ZENKHUOXINGJIBENHUIFU。ZHONGLIUHUANZHEFUYONGDILONGTIQUWU2GEYUE,CAIYONGXILIEKANGRULINBAXIBAOJIQIYAQUNDANKELONGKANGTI(McAb),YONGJIANJIEMIANYIYINGGUANGFAJIANCET3,T4,T8,T4/T8,Tb,Tac,BXIBAOYAQUNDEZHI,FUDILONGTIQUWUZHEKETIGAOT3,T4JIT4/T8JI,TISHIQIWEIYIZHONGMIANYIZENGQIANGJI。JIESHOUFANGSHEZHILIAODESHIGUANAIHUANZHEYANDILONGTIQUWU150mg,MEIRI2CI,NENGKONGZHIHUANZHEBAIXIBAOXIAJIANG,XIAOGUOYOUYUMIANYIZENGQIANGXINGDUOKANGJIASU(polyactin A)。HELIU(S180)XIAOSHUMEIRIGUANFUDILONGTIQUWU100mg/kg,LIANXU7d,NENGSHIYINHELIUERZENGJIAYINGGUANGCHANWU(ZHIJIEFANYINGTINEIZHIZHIGUOYANGHUASULV)HANLIANGJIANGDI,XUEZHONGGUYOUGANTAIHUANYUANMEI(GR)、GUOYANGHUAQINGMEI(CAT)、GUYOUGANTAIGUOYANGHUAWUMEI(GSH-Px)DONGHECHAOYANGHUAWUQIHUAMEI(SOD)DEHUOXINGZEZENGJIA,TISHIDILONGTIQUWUYOUQINGCHUZIYOUJI、KANGZHIZHIGUOYANGHUADEZUOYONG。DANTIWAISHIYANQUEZHENGMING,DILONGTIQUWUYUJIGUANG、XUEXIELINYANSHENGWUDUIS180AIXIBAOJUYOUXIETONGSHASHANGZUOYONG,HUAXUEFAGUANGQIANGDUYEMINGXIANZENGGAO,RUJIANGZIYOUJIQINGCHUJICATHESODJIARUPEIYANGJINEI,ZESHIZENGQIANGDEFAGUANGQIANGDUMINGXIANJIANXIAO,TISHIDILONGTIQUWUDEXIETONGZUOYONGZHISHAOBUFENSHITONGGUOZENGJIAHUOXINGYANGERSHIXIANDE。

657彩票网 北京pk10 5.PINGCHUANZUOYONGTUNSHUFUQIANGZHUSHEDILONGYE(MEI1mlHANXIANDILONGYUE0.75g/ml)2ml,DUILUANDANBAIYINQIDEGUOMINXINGXIAOCHUANQIANFUQIMINGXIANYANCHANG,XIRUZUANYINQIDEXIAOCHUANQIANFUQIYEMINGXIANYANCHANG,DANDUIXIRUYISUANDANJIANYINQIDEXIAOCHUANZEWUYINGXIANG。DASHUFUQIANGZHUSHEDILONGYE2ml,LIANXU3dDUILUANDANBAIYINQIDEBEIDONGPIFUGUOMINFANYINGYOUYIZHIZUOYONG。ZAITIWAI,DILONGYE8×10-7g/mlNONGDUDUITUNSHULITIQIGUANYOUZUANYINQIDESHOUSUOYOUMINGXIANYIZHIZUOYONG。CONGQIUYINTICHUDEHANDANCHENGFENDUIDASHU、JIATUFEIGUANZHUFAYOUXIANZHUKUOZHANGZHIQIGUANZUOYONG,BINGNENGDUIKANGZUANHEMAOGUOMEIXIANGJIANYINQIDEZHIQIGUANSHOUSUO。JINGZHUYUTUNSHU,50%DONGWUKENAISHOUZHISILIANGZUAN。RENWEIDILONGDEMOUZHONGZUFENKEZUZHIZUANSHOUTI,DUIKANGZUANSHIQIGUANJINGLUANJIZENGJIAMAOXIXUEGUANTONGTOUXINGDEZUOYONG,CIWEIPINGCHUANDEZHUYAOJIZHI。

657彩票网 北京pk10 6.DUIPINGHUAJIDEZUOYONGCONGGUANGDILONGTIQUCHUDEDANHUANGSEJIEJING,NENGSHIYIYUNHEWEIYUNDASHUHUOTUNSHULITIZIGONGJINZHANGDUMINGXIANSHENGGAO,NONGDUZENGJIAKESHIZHICHENGJINGLUANSHOUSUOZHUANGTAI;JINGZHU1mg/kg,KESHIJIATUZAIWEIZIGONGJINZHANGDUSHENGGAO,JINGZHU 3~6mg/kgHUOGUANFU 10~20mgl/kg,KESHIMANXINGZIGONGLOUGUANJIATUZIGONGSHOUSUOMINGXIANZENGQIANG。CIWAI,GAIJIEJING0.5~ 1mg/kgJINGZHU,DUIJIAMIANZAIWEICHANGGUANYIYOUMINGXIANXINGFENZUOYONG,DUIDASHUHOUZHIXUEGUANGUANLIUYIBIAOXIANMINGXIANXINGFEN,DANDUIZAITITUNSHUZHIQIGUANZUOYONGJIAORUO。

657彩票网 北京pk10 7.QITAZUOYONGQIUYIN3%CUSUANTIQUWU、2.5%LIUSUANTIQUWU。

84%YICHUNJISHIYOUMITIQUWUZAITIWAIDUIRENXINGJIEHEGANJUNYOUJIAOQIANGYIZHIZUOYONG,YOU3%CUSUANTIQUDELIANGZHONGWUZHIYIZHIRENXINGJIEHEGANJUNDEZUIXISHIWEISHUFENBIEWEI100XINJI70BEI,2.5%LIUSUANTIQUWUDEZUIGAOXISHIBEISHUWEI100BEI,CISANZHONGTIQUWUJUNNAIRE; 84%YICHUNJIWUYOUMITIQUWUDEZUIGAOXISHIBEISHUJUNWEI3200BEI,DANBUNAIRE。

657彩票网 北京pk10 DILONGTIQUWUZAITIWAIDUIXIAOSHUHERENDEJINGZIJUNYOUKUAISUSHAMIEZUOYONG,QIZHONGDETUIPAISUAN、TOUMINGZHISUANNENGXUNSUSHIJINGZIZHIDONG、NINGJI,BINGSHIQIJIEGOUSHOUDAOPOHUAI。

657彩票网 北京pk10 DILONGTIQUYEWAIYONGDUIJUXIANXINGYINGPIBINGYOUXIAO,JINGSHENGHUAFENXITIQUWUJUYOUTEYIXINGJIANGJIEJIAOYUANXIANWEIDEJIAOYUANMEI,QILIAOXIAOHENKENENGSHIJUBUBIANXINGJIAOYUANXIANWEIJIANGJIESUOZHI。

8.TINEIGUOCHENGJIATUJINGZHUCANBEIMAOYINZHUSHEYE,YININGXUEMEISHIJIANCEDINGWEIYAOXIAOZHIBIAO,ANYAOXIAOYIDUISHUJILIANGGUANXIGUSUANYAODONGXUECANSHU,BIAOMINGQIKANGNINGXUEMEIYOUXIAOCHENGFENZAITINEISHUYIJIDONGLIXUEXIAOCHU,FUHEERSHIMOXING,t1/2a。WEI4.1limn,t1/2βWEI140min,LIANGXIAOQUXIANXIAMIANJI(AUC)WEI169.1mg/(kg·h),QINGCHULV(CL)WEI0.964h-1。TISHIKANGNINGXUEMEICHENGFENYOUXUEYEXIANGWAIZHOUZUZHIFENBUSULVHENKUAI,ERQINGCHUJIAOMAN,KENENGSHIYIZHONGXIAOFENZIWUZHI,ZAITINEIFENBUGUANGFAN。

9.DUXINGGUANGDILONGREJINJIGEIXIAOSHUJINGZHULD50。WEI3.85g/kg,FUQIANGZHUSHELD50。WEI95-115gl/kg,GEIDASHUGUANWEI0.lgl/(kg·d),LIANXU45dWEIFAXIANDUXINGFANYING。XIAOSHUFUQIANGZHUSHEGUANGDILONGZHUSHEYE,LD50WEI40.7g/kg。CONGGUANGDILONG 1000gTIDEDANHUANGSEJIEJING 2g,GEIXIAOSHUWEIZHU LD50。WEI 38.7mg/kg。ANDONGWUJIXINGSIWANGLVFAGUCECANHUAIMAOYINDUXINGZUFENDEYAODONGXUECANSHU,QIZAITINEISHUYIJIDONGLIXUEXIAOCHU,CHENGYISHIMOXING,t1/2。WEI31.2min,JINWEIKANGNINGXUEMEICHENGFENXIAOCHUBANSHUAIQIDE22.3%,YINDUXINGZUFENBANSHUAIQIDUAN,SUOYIDILONGDUOCILIANXUGEIYAOBUYIZAOCHENGXUJIZHONGDU。BIJIAOANQUAN。

【PAOZHI】CHUQUZAZHI,XIJING,QIEDUAN,GANZAO。

【XINGWEI】WEIXIAN;XINGHAN

【GUIJING】GUIGAN;PI;BANGGUANGJING

657彩票网 北京pk10 【GONGNENGZHUZHI】QINGSHIZHIJING;PINGGANXIFENG;TONGJINGHUOLUO;PINGCHUANLINIAO。ZHUREBINGFAREKUANGZAO;JINGXIANCHOUCHU;GANYANGTOUTONG;ZHONGFENGPIANTAN;FENGSHIBITONG;FEIRECHUANKE;XIAOBIANBUTONG

【YONGFAYONGLIANG】NEIFU:JIANTANG,5-10g;HUOMO,MEICI1-2g;HUORUWAN、SAN;HUOXIANPINBANTANGHUOYANHUASHUIFU。WAIYONG:SHILIANG,XIANPINDAOLANFUHUOQUZHITUFU;YANMOSAHUODIAOTU。

657彩票网 北京pk10 【ZHUYI】PIWEIXUHANBUYIFU,YUNFUJINFU。

657彩票网 北京pk10 【LINCHUANGYINGYONG】YONGYUGAORESHENHUN,JINGXIANCHOUCHU,GUANJIEBITONG,ZHITIMAMU,BANSHENBUSUI,FEIRECHUANKE,NIAOSHAOSHUIZHONG;GAOXUEYA。

【ZHAILU】《ZHONGHUABENCAO》

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