657彩票网 北京pk10

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中醫藥大全 > 藥材 > 中藥材 > J > 絞股藍

絞股藍

2017-08-15 10:38 作者:老中醫 閱讀:

《全國中草藥匯編》:絞股藍

【YAOCAIMINGCHENG】JIAOGULAN

657彩票网 北京pk10 【PINYIN】Jiǎo Gǔ Lán

【BIEMING】QIXIEDAN、XIAOKUYAO、GONGLUOGUODI

【來源】葫蘆科絞股藍屬植物絞股藍Gynostemma pentaphyllum (Thunb.)Makino,以根狀莖657彩票网 北京pk10入藥。秋季采集,洗凈曬干,研粉。

657彩票网 北京pk10 【XINGWEI】KU,HAN。

【GONGNENGZHUZHI】QINGREJIEDU,ZHIKEQUTAN。YONGYUMANXINGZHIQIGUANYAN,CHUANRANXINGGANYAN,SHENYANYAN,WEICHANGYAN。

【YONGFAYONGLIANG】0.75~1KE(SANJI)。

657彩票网 北京pk10 【ZHAILU】《QUANGUOZHONGCAOYAOHUIBIAN》

 

《中藥大辭典》:絞股藍

657彩票网 北京pk10 【YAOCAIMINGCHENG】JIAOGULAN

【PINYIN】Jiǎo Gǔ Lán

【YINGWENMING】Herba Gynostemmatis Pentaphylli

【BIEMING】QIXIEDAN

【來源】為葫蘆科植物絞股藍Gynostemma pentaphyllum (Thunb.)Mak.的全草。秋季采收,曬干。

【YUANXINGTAI】DUONIANSHENGPANYUANCAOBEN。JINGXICHANG,JIESHANGYOUMAOHUOWUMAO,JUANXUCHANG2LIEHUOBUFENLIE。XIENIAOZUZHUANG,CHANGYOU5~7XIAOXIEZUCHENG,XIAOXIEPIANCHANGTUOYUANZHUANGPIZHENXINGZHILUANXING,YOUXIAOXIEBING,ZHONGJIANXIAOXIEPIANCHANG3~9cm,KUAN1.5~3cm,BIANYUANYOUJUCHI,BEIMIANHUOYANLIANGMIANXIEMOYOUDUANGANGMAOHUOJINWUMAO。YUANZHUIHUAXU;HUAXIAO,ZHIJINGYUE3mm;HUAELIEPIANSANJIAOXING,CHANGYUE0.5mm;HUAGUANLIEPIANPIZHENXING,CHANGYUE2mm。GUOQIUXING,CHENGSHUSHIHEISE。HUAQI7~8YUE,GUOQI9~10YUE。

【SHENGJINGFENBU】SHENGYUSHANJIANYINSHICHU。CHANYUANHUI、ZHEJIANG、JIANGXI、FUJIAN、GUANGDONG、GUIZHOU。XIANGEDIDUOYOUZAIPEI。

【HUAXUECHENGFEN】HANJIAOGULANZAODAI(aypenoside)1~52,QIZHONG3、4、8、12FENBIEYURENCANZAODAI(Rb1、Rb3、Rb、Rf2JIEGOUXIANGTONG,LINGHANYOUHUANGTONG、TANGLEI。

657彩票网 北京pk10 【XINGWEI】XINGHAN,WEIKU。

【GONGNENGZHUZHI】XIAOYANJIEDU,ZHIKEQUTAN。XIANDUOYONGZUOZIBUQIANGZHUANGYAO。

657彩票网 北京pk10 【ZHAILU】《ZHONGYAODACIDIAN》

絞股藍http://yeanja.com/tp/14205.html
絞股藍 http://yeanja.com/tp/14205.html


《中華本草》:絞股藍

657彩票网 北京pk10 【YAOCAIMINGCHENG】JIAOGULAN

【PINYIN】Jiǎo Gǔ Lán

【BIEMING】QIXIEDAN、XIAOKUYAO、GONGLUOGUODI、LUODISHENG、BIANDISHENGGEN

【CHUCHU】JIAOGULANSHIZAIYU《JIUHUANGBENCAO》,YUN:"JIAOGULAN,SHENGTIANYEZHONG,YANMANERSHENG,XIESIXIAOLANXIE,DUANXIAOJIAOBO,BIANYOUJUCHI,YOUSILIJIANCAO,XIEYIRUAN,DANLV,WUXIEZANSHENGYICHU,KAIXIAOHUA,HUANGSE,YIYOUKAIBAIHUAZHE,JIEZIRUWANDOUDA,SHENGZEQINGSE,SHUZEZIHEISE,XIEWEITIAN。"JUQISHENGCHANGHUANJINGJIXINGTAITEZHENG,QISUOSHUJIBENZHONG。

【LAIYUAN】YAOCAIJIYUAN:WEIHULUKEZHIWUJIAOGULANDEQUANCAO。

657彩票网 北京pk10 LADINGZHIWUDONGWUKUANGWUMING:Gynostemma pentaphyllum(Thunb.)Makino

CAISHOUHECHUZANG:MEINIANXIA、QIULIANGJIKECAISHOU3-4CI,XIJING、SHAIGAN。

657彩票网 北京pk10 【YUANXINGTAI】JIAOGULAN DUONIANSHENGPANYUANCAOBEN。JINGXIRUO,DUOFENZHI,JUZONGLENGHEGOUCAO,WUMAOHUOSHUBEIDUANROUMAO。XIEHUSHENG;XIEBINGCHANG3-7cm;JUANXUXIANXI,2QI,XIDANYI,WUMAOHUOJIBUBEIDUANROUMAO;XIEPIANMOZHIHUOZHIZHI,NIAOZUZHUANG,JU5-9XIAOXIE,TONGCHANG5-7,LUANZHUANGCHANGYUANXINGHUOCHANGYUANZHUANGPIZHENXING,ZHONGYANGXIAOXIECHANG3-12cm,KUAN1.5-4cm,CESHENGXIAOXIEJIAOXIAO,XIANDUANJIJIANHUODUANJIANJIAN,JIBUJIANXIA,BIANYUANJUBOZHUANGCHIHUOYUANCHIZHUANGYACHI,SHANGMIANSHENLVSE,BEIMIANDANLVYI,LIANGJIANXIA,BIANYUANJUBOZHUANGCHIHUOYUANCHIZHUANGYACHI,SHANGMIANSHENLVYI,BEIMIANDANLVSE,LIANGMIANJUNBEIDUANYINGMAO;CEMO6-8DUI,SHANGMIANPINGTAN,XIAMIANTUQI,XIMOWANGZHUANG。CIXIONGYIZHU,XIONGHUAWEIYUANZHUIHUAXU,HUAXUSUIXIANXI,DUOFENZHI,CHANG10-15(-20)cm,FENZHIKUOZHAN,CHANG3-4(-15)cm,YOUSHIJIBUJUXIAOXIE,BEIDUANROUMAO,HUAGENGSIZHUANG,CHANG1-4mm;JIBUJUZHANZHUANGXIAOBAOPIAN;HUAETONGJIDUAN,5LIE,LIEPIANSANJIAOXING;HUAGUANDANLVYI,5SHENLIE,LIEPIANLUANZHUANGPIZHENXING,CHANG2.5-3mm,KUANYUE1mm,JU1MO,BIANYUANJUYUANMAOZHUANGXIAOCHI;XIONGRUI5,LIANHECHENGZHU;CIHUAWEIYUANZHUIHUAXU,JIAOXIONGHUAXIAO,HUAE、HUAGUANJUNSIXIONGHUA;ZIFANGQIUXING,HUAZHU3DUANERFENCHA,ZHUTOU2LIE,JUDUANXIAOTUIHUAXIONGRUI5。GUOSHIQIUXING,JING5-6mm,CHENGSHUHOUWEIHEISE,GUANGHUAWUMAO。NEIHANDAOCHUIZHONGZI2KE,LUANZHUANGXINXING,JINGYUE4mm,HUIHESEHUOSHENHESE,DINGDUANDUN,JIBUXINXING,YABIANZHUANG,MIANJURUTUZHUANGTUQI。HUAQI3-11YUE,GUOQI4-12YUE。

【SHENGJINGFENBU】SHENGTAIHUANJING:SHENGYUHAIBA100-3200DESHANGUMILINZHONG、SHANPOSHULINXIAHUOGUANCONGZHONG。

ZIYUANFENBU:FENBUYUSHANXI、GANSUHECHANGJIANGYINANGEDI。

【ZAIPEI】SHENGWUXUETEXING XIWENNUANQIHOU。XIYINSHIHUANJING、JILIERIZHISHE,NAIHANXINGCHA。DUITURANGTIAOJIANYAOQIUBUYANGE,YIXUANZESHANDILINXIAHUOYINPOSHANGUZHONGZHI,YIFEIWO、SHUSONGDESHARANGTUWEIHAO。

657彩票网 北京pk10 ZAIPEIJISHU YONGZHONGZI、GENJINGFENDUANHEJINGMANQIANCHAFANZHI。ZHONGZIFANZHI:YONGZHIBOHEYUMIAOYIZAIFA。ZHIBOFA,BOQI3-4YUE,ANXINGJU40cmKAIGOUTIAOBO,FUTU1cm。CHUMIAOHOUGAO15cmSHI,ANZHUJU15-20mJIANMIAO、DINGMIAO。YUMIAOYIZAIFA,JIANGJINGJINZHONGDEZHONGZIZAIMIAOCHUANGSHANGSABO,MIAOCHANGCHU2-3PIANZHENXIESHI,ANXINGZHUJU40cm×mYUYINTIANYIZAIJINDATIAN。GENJINGFENDUANFANZHI:3-4YUE,JIANGGENJINGWACHU,JIANCHENGCHANGYUE5cmXIAODUAN,MEIDUANYOU1-2JIE,ANXINGZHUJU50cm×30cmKAIXUE,MEIXUEFANGRU1XIAODUAN,FUTUYUE3cm,1hm2ZAI45000ZHUZUOYOU,ZAIHOUJISHIJIAOSHUIBAOSHI。JINGMANQIANCHAFANZHI:5-7YUE,BADISHANGJINGMANJIANXIACHENGDUAN,MEIDUANBAOLIU3-4JIE,QUDIAOXIAMIAN2JIEXIAOXIE,ANXINGZHUJU10cm×10cmXIECHARUMIAOCHUANG,JIAOSHUIBAOSHI,DAICHANGCHUXINGENHEXINYACHANGZHI10-15cmSHI,ANXINGZHUJU30m×15cmKAIXUEZHIRUDATIAN。

TIANJIANGUANLI MIAOQIZHUYISONGTUCHUCAO,QINJIAOSHUI,ZHEYINBIFENG。YIBANKEDA2GAOPENGJIAZHEYIN,PENGXIAYONGZHUGANCHARENZIXINGZHIJIA,YINMANCHANRAOSHENGCHANG。ZAILINXIAZHONGZHI,BUXUDAPENGJIA,RENQIPUFUDIMIANSHENGCHANGHUOPANYUANTAWUSHENGCHANG。MIAOQIZHUIFEI1CI,SHENGCHANGSHENGQIZHUISHIFUHEFEI2-3CI,MEICIMEI1hm2SHI105-180g。MEICISHOUGEHOUDOUXUZHUIFEI1CI。PINGSHIZHUYIJIAOSHUIBAOSHI,BIMIANGANHAN,YUJIZHUYIPAISHUIFANGLAO。

【XINGZHUANG】XINGZHUANGJIANBIE BENPINWEIGANZAOZHOUSUODEQUANCAO,JINGXIANXIHUIZONGSEHUOANZONGSE,BIAOMIANJUZONGGOUWEN,BEIXISHUMAORONG,RUNSHIZHANKAIHOU,XIEWEIFUXIE,XIAOXIEMOZHI,TONGCHANG5-7MEI,SHAOSHU9MEI,XIEBINGCHANG2-4cmBEICAOMAO;CESHENGXIAOXIELUANZHUANGCHANGYUANXINGHUOCHANGYUANZHUANGPIZHENXING,ZHONGYANG1MEIJIAODA,CHANG4-12cm,KUAN1-3.5cm;XIANDUANJIANJIAN,JIBUXIEXING,LIANGMIANBEICUMAO,XIEYUANYOUJUCHI,CHIJIANJUMANG。CHANGKEJIANDAOGUOSHI,YUANQIUXING,ZHIJINGYUE5mm,GUOGENGCHANG3-5mm。WEIKU,JUCAOXINGQI。

XIANWEIJIANBIE XIEHENGQIEMIAN:XIEDESHANGXIABIAOPIYOU1CENGCHANGFANGXINGXIBAOZUCHENG,WAIBEIJIAOZHICENG。XIEROUZUZHIYIMIANXING,ZHALANZUZHIYOU1-2CENGXIBAOZUCHENG,BUTONGGUOZHUMO;HAIMIANZUZHIYOU3-4CENGXIBAOZUCHENG。ZHUMOJUNXIANGSHANGXIABIAOPITUCHU,NEICEYOU2-3CENGHOUJIAOXIBAO,WEIGUANSHUWAIRENXING。 XIEBIAOMIAN:SHANGBIAOPICHUIZHOUBIJINPINGZHI,XIABIAOPICHUIZHOUBIWEIBOZHUANGWANQU,QIKONGWEIBUDINGSHI。SHANGXIABIAOPIJUNYOUFEIXIANMAOHEXIANMAO;FEIXIANMAOYOU5-14GEXIBAOZUCHENG,BIAOMIANYOUMINGXIANDEXIANZHUANGJIAOZHIZONGWEN,CHANG120-360mm。

JINGHENGQIEMIAN CHENGDUOJIAOXING,BIAOPIYOU1LIEBIANPINGDEXIBAOZUCHENG,WAIBIJIAOZHIZENGHOU,ZHUSHENGDANXIBAOHEDUOXIBAOFEIXIANMAO,JIAOYUCHUYOUHOUJIAOZUZHI,YOU4-6LIEXIBAOZUCHENG;PICENGNEIFANGYOUWEIRAOYURENPIBUWAIYUANDEBANYUEXINGXIANWEIJIAN,NEIFANGYOU9-10GEDAXIAOBUDENGDESHUANGRENWEIGUANSHU,FANGSHEPAILIE;LIANGRENPISHEXIANJIANYOUSHIXIBAOQUN;SUIBUBOBIXIBAONEIHANYOUZHIJING12-28mmDEDIANFENLI。

【HUAXUECHENGFEN】1.JIAOGULANTANGDAI(gynosaponin)TN-1HETN-2;JIAOGULANDAI(gypenoside)I→LXXIXGONG79GE,QIZHONGⅢ、Ⅳ、Ⅷ、ⅦJIJIEGOUHERENCANZAODAI(gensenoside)-Rb1、Rb3、Rd、F2DEXIANGTONG;6"-BINGERXIANJIRENCANZAODAI(6"-malonylgensenoside)-Rb1HERd,6"-BINGERXIANJIJIAOGULANDAIV(6"-malonylgypenoside V)DENG。ZHEXIEZAODAIDEDAIYUANYOU:RENCANERCHUN(panaxadiol),2α-QIANJIRENCANERCHUN(2α-hydroxy-panaxadiol),(20R,25S)-12β,25-HUANYANG-20,26-HUANDAMAWAN-3β-CHUN[(20R,25S)-12β,25-epoxy-20,26-cyclodammaran-3β-ol],(20R,25S)-12β,25-HUANYANG-20,26-HUANDAMAWAN-2α,3β-ERCHUN[(20R,25S)-12β, 25-epoxy-20,26-cyclodammaran-2α,3β-diol],JIAOGULANDAIYUANⅡ(gynogeninⅡ)JISHI(20R)-21,24-HUAN-3β,25-ERQIANJI-23(24)-DAMAXI-21-TONG[(20R)-21,24-cyclo-3β,25-dihydroxydammar-23(24)-en-21-one]。

2.ZUIJIN,YOUDEDAO4GEXINDEDAMAWANXINGZAODAI,TAMENSHI:(20S)3β,20,23ζ-SANQIANJI-24-DAMAXI-21-SUAN-21,23-NEIZHI-3-O-[β-D-BINANPUTAOTANGJI(1→2)-α-L-BINANALABOTANGJI]-20-O-β-D-BINANSHULITANGDAI[(20S)3β,20,23-trihydroxydammar-24-en-21-oic acid-21,23-lactone-3-O-[β-D-glucopyranosyl(1→2)-α-L-α-L-arabino-pyranosyl]-20-O-β-D-rhamnopyranoside]YIJITADE(20R)CHAXIANGYIGOUTI(epimer),(20S)-23ζ-DAMAXI-3β,20,25,26-SICHUN-3-O-[β-D-BINANPUTAOJI-(l→2)-α-L-BINANALABOTANGJI]-20-O-β-D-BINANSHULITANGJI-26-O-BINANPUTAOTANGDAI[(20S)-dammar-23-ene-3β,20,25,26-tetraol-3-O-[β-D-glucopyranosyl(1→2)-α-L-arabinopyranosyl]-20-O-β-D-rhamnopyranosyl-26-O-glucopyranoside],(20R)-25-DAMAXI-3β,20,21,24ζ-SICHUN-3-O-[β-D-BINANPUTAOTANGJI-(1→2)-α-L-]BINANALABOTANGJI]-21-O-β-D-BINANPUTAOTANGJI-24-O-BINANSHULITANGDAI[(20R)-dammar-25-en-3β,20,21,24-ζ-tetraol-3-O-[β-D-glucopy-ranosyl-(1→2)-α-L-arabinopyranosyl]-21-O-β-D-glucopyranosyl-24-O-rhamnopyranoside]。

3.HUANHANZAICHUNLEICHENGFEN:5,24-HULUERXICHUN(cucurbita-5,24-dienol),24,24-ERJIAJI-5α-DANZAI-8-XI-3β-CHUN(24,24-dimethyl-5α-cholest-8-en-3β-ol),(24R)-5α-DOUZAI-7-XI-22-GUI-3β-CHUN[(24R)-5α-stigmast-7-en-22-yn-3β-ol],24,24-ERJIAJI-5α-DANZAI-7-XI-22-GUI-3β-CHUN(24,24-dimethyl-5α-cholest-7-en-22-yn-3β-ol),24,24-ERJIAJI-5α-DANZAI-7, 25-ERXI-22-GUI-3β-CHUN(24,24-dimethyl-5α-cholesta-7,25-dien-22-yn-3β-ol),BOCAIZAICHUN(spi-nasterol),α-BOCAIZAICHUN(α-spinasterol,chondrillaierol),24,24-ERJIAJI-5α-DANZAI-7-XI-3β-CHUN-(24,24-dimethyl-5α-cholest-7-en-3β-ol),(22E)-24,24-ERJIAJI-5α-DANZAI-7,22-ERXI-3β-CHUN[(22E)-24,24-dimethyl-5α-cholesta-7,22-dien-3β-ol],24,24-ERJIAJI-5α-DANZAI-7,25-ERXI-3β-CHUN(24,24-dimethyl-5α-cholesta-7,25-dien-3β-ol),14α-JIAJI-5α-MAIJIAOZAI-9(11),24(28)-ERXI-3β-CHUN[14α-methyl-5α-ergosta-9(11),24(28)-dien-3β-ol],24,24-ERJIAJI-5α-DANZAI-3β-CHUN(24,24-dimethyl-5α-cholestan-3β-ol),24α-YIJI-5α-DANZAI-3β-CHUN(24α-ethyl-5α-cholestan-3β-ol), 14α-JIAJI-5α-MAIJIAOZAI-9(11)-XI-3β-CHUN[14α-methyl-5α-ergost-9(11)-en-3β-ol]DE(24R)HE(24S)DECHAXIANGYIGOUTI,4α,14α-ERJIAJI-5α-MAIJIAOZAI-7,9(11),24(28)-SANXI-3β-CHUN[4α,14α-dimethyl-5α-ergosta-7,9(11),24(28)-trien-3β-ol],YIYANZAOZAICHUN(isofucosterol),β-GUZAICHUN(β-sitosterol)DENG。

4.YOUHANHUANGTONGLEICHENGFEN:YUNXIANGDAI(rutin),SHANGLUDAI(om-buoside),SHANGLUHUANGSU(ombuin); BINGERSUAN(malonic acid),WEISHENGSUC(vitamin C);TIANDONGANSUAN(aspartic acid),SUANSUAN(threonice),SIANSUAN(serine),GUANSUAN(glutamic acid)DENG17ZHONGANJISUANHETIE、XIN、TONG、MENG、NIEDENG18ZHONGYUANSU。LINGHANTIANWEICHENGFEN:XIETIANSU(phyllodulcin)。

657彩票网 北京pk10 【YAOLIZUOYONG】1.DUIMIANYIGONGNENGDEYINGXIANG:1.1.DUIFEITEYIXINGMIANYIDEYINGXIANG:XIAOSHUGUANFUJIAOGULANJIANJI10g/kgHUO30g/kg,LIANFU10RI,KEMINGXIANZENGJIAPIZANGZHONGLIANG,TIZHONGYIBIDUIZHAOZUMINGXIANZENGJIA,NENGMINGXIANCUJINDANHEJUSHIXIBAOXITONGDUIXUEZHONGJIAOTITANDEKUOQINGSULV,TIGAODANHEXIBAODETUNSHIGONGNENG,30g/kgJILIANGYIKESHIXIONGXIANZHONGLIANGZENGJIA。LINGYOUBAODAO,ZHENGCHANGXIAOSHUGUANFUJIAOGULANZONGZAODAI(GPs)50mg/kg,LIANFU10RI,DUIPIZHONGCHENGSHUANGXIANGDIAOJIEZUOYONG,JIDUIYUXIAOYUZHONGWEISHUDEPIZHONG(mg/10gTIZHONG)KESHIZHIZENGJIA,DAYUZHONGWEISHUDEPIZHONGZESHIZHIJIANXIAO;DUIXIONGXIANZHONGLIANG(mg/10gTIZHONG)XIAOYUZHONGWEISHUZHEWUMINGXIANYINGXIANG,DAYUZHONGWEISHUZHEYIKESHIZHIMINGXIANJIANXIAO。XIAOSHUGUANFUGPs200mg/kgHUO400mg/kg,LIANFU10RI,KEMINGXIANDUIKANGHUANLINXIANANYINQIDEXIONGXIANHEPIZANGZHONGLIANGJIANQING。XIAOSHUGUANFUJIAOGULANSHUIJIANCHUNCHENSHUITIWU0.5g/kg、1g/kgHE2g/kg,LIANFU5RI,KEZENGJIAXIONGXIANZHONGLIANG,1.0g/kgJI2.0g/kgSHICAINENGZENGJIAPIZHONG。XIAOSHUGUANFUGPs400mg/kg,LIANFU5RI,DUIHUANLINXIANANSUOZHIXIONGXIAN、PIZANGHECHANGXIMOLINBAJIEZHONGLIANGDEJIANQINGYOUMINGXIANJIEKANGZUOYONG,DANDUIZHENGCHANGDONGWUMIANYIQIGUANZHONGLIANGZEWUMINGXIANYINGXIANG。YIYOUBAODAO,XIAOSHUGUANFUGPs300mg/kg,LIANFU7RI,DUITIZHONG、PIZANGHEXIONGXIANZHONGLIANGJUNWUMINGXIANYINGXIANG,DANNENGXIANZHUJIAQIANGFUQIANGJUSHIXIBAOTUNSHIGONGNENG。α-BANRUTANGYOUFADEXIAOSHUYAJIXINGSHUAILAOMOXING,GUANFU3%JIAOGULANJINGAO(HANSHENGYAO150%)HUNXUANYE,LIANFU50RI,KESHIMINGXIANSHENGGAODEBAIXIBAOZONGSHU、LINBAXIBAODEBAIFENLVJIANGDIZHIJIEJINDUIZHAOZU;SHIJIANGDIDEZHONGXINGLIXIBAOBAIFENLVSHENGGAOZHIJIEJINDUIZHAOZU;MOXINGZUXIONGXIANWEISUO,PIZHONGZENGJIA,YONGYAOHOUXIONGXIANZHISHUHUIFU,BINGCHAOGUODUIZHAOZU,PIZHISHUYEHUIFUZHENGCHANG;MOXINGZUXUEQINGRONGJUNMEIHANLIANGXIANZHUJIANGDI,TISHIJITIKANGGANRANLIXIAJIANG,FUYAOZURONGJUNMEIHANLIANGXIANZHUZENGJIABINGCHAOGUODUIZHAOZU。XIAOSHUGUANFUGPs60mg/kgHUO100mg/kg,LIANFU7RIKEMINGXIANTIGAOWAIZHOUXUEBAIXIBAOSHU,BINGZENGQIANGQITUNSHIJIAOMUDUOTANGSHIDEHUAXUEFAGUANGFENGZHI,TONGSHIFAGUANGZHISHU(FAGUANGFENGZHI/BAIXIBAOSHU)YEMINGXIANTIGAO:DUICUSUANPONISONGYOUFAMIANYIYIZHIDEXIAOSHUGUANFUGPs80mg/kgHUO120mg/kg,LIANFU7RI,BAIXIBAOSHU、FAGUANGFENGZHIHEFAGUANGZHISHUDETIGAOGENGWEIXIANZHU,TISHIGPsBUJINNENGSHENGGAOZHENGCHANGDONGWUBAIXIBAOSHU,ERQIENENGSHIYIXIEBAIXIBAOSHUDIXIADEDONGWUBAIXIBAOSHUHUISHENG,ZENGQIANGZHENGCHANGHUOGONGNENGDIXIADEBAIXIBAOTUNSHIGONGNENG。LINGYOUBAODAODASHUKOUFUHANJIAOGULANJIANJIDESILIAO20g/kg,LIANFU15RI,DUIFEIJUSHIXIBAOTUNSHIGONGNENGYOUMINGXIANYIZHIZUOYONG。

657彩票网 北京pk10 1.2.DUILINBAXIBAOZHUANHUAHEBAIJIESU-2(IL-2)FENMIDEYINGXIANG:JIAOGULANSHUIJIANCHUNCHENSHUITIWU10μml、100μg/mlJI1000μg/mlSHI,JUNKETIGAODAODOUQIUDANBAIA(ConA)JIZHIDUOTANG(LPS)YOUDAODEXIAOSHUPIZANGHELINBAXIBAODEZENGZHIFANYING。GPs10-200μg/mlNENGCIJIDASHUHEXIAOSHUPILINBAXIBAOZIFAXING[3H]XIONGXIANMIDINGHEGAN(H3-TdR)CHANRU,YUCIYASHILIANGConAPEIWU,KEXIETONGCIJIXIAOSHUPILINBAXIBAOCHANRU;ZAITIWAI,HUANNENGCIJIDASHUPILINBAXIBAOZIFAFENMIIL-2。LINGYOUBAODAO,GPsXIAOJILIANG2.5-20μg/mlCUJINXIAOSHUPIZANGTHEBLINBAXIBAOZHUANHUA,BINGTIGAODNADUOJUMEIⅡHUOXING,CUJINLINBAXIBAODNAHECHENG,DANDAJILIANGGPs(>40g/ml)ZECHENGXIANGFANZUOYONG,GPs40μg/ml、80μg/mlDUIConA、LPSHEZHIWUXUENINGSU(PHA)YOUFADEXIAOSHUPIXIBAOZENGZHIFANYINGYOUMINGXIANCUJINZUOYONG;YEZENGQIANGDASHUPIXIBAOIL-2DEFENMI。ZHENGCHANGXIAOSHUPIXIAZHUSHEGPs10mg/HUO30mg/kg,LIANXU7TIAN,DUIConAHELPSYOUDAODEPIZANGTHEBLINBAXIBAOZENGZHIFANYINGJUNYOUZENGQIANGZUOYONG,YI10mg/kgZUZUOYONGGENGXIANZHU,HUANKETIGAOPIXIBAOIL-2DESHENGCHENGLIANG,YI30mg/kgZUZUOYONGGENGMINGXIAN。DUIHUANLINXIANANSUOZHIMIANYIGONGNENGDIXIAXIAOSHU,PIXIAZHUSHEGPs10mg/kgHUO20mg/kg,LIANXU7TIAN,DUISHANGSHUSANXIANGZHIBIAOJUNMINGXIANZENGGAO,DANIL-2DEZENGGAOCHUXIANZUIZAO,TXIBAOZENGZHIFANYINGZENGQIANGCHUXIANJIAOWAN。20mg/kgZUZUOYONGGENGXIANZHU。ZONGDEKANLAI,GPsDUIMIANYIGONGNENGDIXIAXIAOSHUDEZUOYONGGENGXIANZHU。DASHUFUQIANGZHUSHEGPs10mg/kgHUO20mg/kg,LIANXU7TIAN,PIXIBAODUIConAYOUDAODEZENGZHIFANYINGMINGXIANZENGQIANG,YI10mg/kgZUGENGWEIXIANZHU。TONGSHIYIGAOXIAOYEXIANGSEPUJIANCEDANANLEISHENJINGDIZHI,JIEGUOBIAOMING,XIAQIUNAOQUJIASHENSHANGXIANSU(NE)HANLIANGXIAJIANG,PIZANGYIMINGXIANJIANGDI,YUPIXIBAOZENGZHIFANYINGCHENGFUXIANGGUAN;CIWAI,XUEJIANGPIZHITONGSHUIPINGYIXIAJIANG。JIEGUOTISHI,GPsDUIMIANYIFANYINGDEYINGXIANG,YUZUOYONGYUSHENJINGNEIFENMIDIAOJIEWANGLUO,JINERFAHUIMIANYIZENGQIANGZUOYONGJUYOUMIQIEGUANXI。GPs10-80μg/mlKEXIETONGConASHIZHENGCHANGXIAOSHUPIXIBAOCHANSHENGZHIIL-2MINGXIANTIGAO;ZHENGCHANGXIAOSHUFUQIANGZHUSHEGPs100-200μg/kg,LIANXU8TIAN,YIKEXIETONGCondSHIPIXIBAOCHANSHENGIL-2MINGXIANTIGAO;DAHUANGYOUFADEXIAOSHUPIXUMOXING,IL-2HUOXINGBIZHENGCHANGXIAOSHUMINGXIANJIANGDI,GPsZAITIWAI、TINEIJUNKEXIETONGConA,SHIDIXIADEIL-2HUOXINGTIGAO,BINGHUIFUZHIJIEJINZHENGCHANGSHUIPING。ZAITIWAI,GPs10μg/mlDUIPHAYOUFADELAONIANRENLINYIXIBAOZENGZHIFANYINGYOUXIANZHUZENGQIANGZUOYONG,NONGDUZAIZENGJIAHUOJIANGDIZEFANYOUYIZHIZUOYONG,RENWEIGPsYOUSHUANGXIANGDIAOJIEZUOYONG,LAONIANRENLINBAXIBAODUIPHAYOUFADEZENGZHIFANYING,QIMINGANXINGJIAOQINGNIANRENLINBAXIBAODI,DANGLINBAXIBAODUIPHAZENGZHIFANYINGJIAODISHI,GPsYOUZENGQIANGZUOYONG,ERDANGLINBAXIBAODUIPHAZENGZHIFANYINGJIAOQIANGSHI,GPsZEWEIYIZHIZUOYONG。MOUXIEEXINGZHONGLIUBINGRENSHUHOUHUOFANGLIAOHOUFUJIAOGULANCHONGJI(MEIBAOHANRENCANZAOER40mg),MEIFU2BAO,MEIRI3CI,LIANFU1YUE,DUILINBAXIBAOZHUANHUAGONGNENG(3H-TdRCHANRU)YOUXIANZHUJIAQIANGZUOYONG,DANIgG、IgMZEMINGXIANJIANSHAO。

1.3.DUITIYEMIANYIGONGNENGDEYINGXIANG:XIAOSHUGUANFUJIAOGULANJIANJI10g/kgHUO50g/kg,LIANFU8TIAN,KEMINGXIANTIGAOXUEQINGZHONGDUIMIANYANGHONGXIBAO(SRBC)TEYIXINGKANGTIRONGXUESUDEHANLIANG。XIAOSHUGUANFUJIAOGULANSHUIJIANCHUNCHENSHUITIWU0.5g/kg、1.0g/kgHUO2.0g/kg,LIANFU5TIAN,DUISRBCMIANYIXIAOSHUNENGCUJINPIZANGKANGTIFENMIXIBAO(PFC)DEXINGCHENG,2g/kgCAINENGCUJINRONGXUESUDEXINGCHENG。XIAOSHUGUANFUGPs100μg/kg,LIANFU10TIAN,DUISRBCMIANYIXIAOSHURONGXUESUSHUIPINGCHENGSHUANGXIANGDIAOJIEZUOYONG,DUIHUANLINXIANANYINQIDERONGXUESUSHUIPINGXIAJIANGYOUMINGXIANDUIKANGZUOYONG,DANWEIHUIFUZHIZHENGCHANGSHUIPING。LINGYOUBAODAOXIAOSHUGUANFUGPs400mg/kg,LIANFU5TIAN,DUIZHENGCHANGDONGWUSRBCYOUFADERONGXUESUWUMINGXIANYINGXIANG,DANDUIHELIU(ROULIU180)XIAOSHUHUODISAIMISONGYOUFADEMIANYIGONGNENGDIXIADASHU,SRBCCHANSHENGDERONGXUESUHEPFCJIANSHAO,GUANFUGPsJUNYOUXIANZHUDEBAOHUZUOYONG。XIAOSHUGUANFUGPs300mg/kg,LIANFU7TIAN,KEXIANZHUSHENGGAOXUEQINGIgGHANLIANG,GUANGXILINGYIDIQUSUOCHANJIAOGULANFENLIDEGPsZESHIIgGHE1gMHANLIANGJUNXIANZHUSHENGGAO。SHANGYOUBAODAO,XIAOSHUGUANFUJIAOGULANJIANJI29g/kg,LIANFU25TIAN,KEJIANGDIPIZANGKANGTIXINGCHENGXIBAOSHU,HUANKEJIANGDIXIAOSHUWAIZHOUXUEKANGSRBCKANGTIDIDU。

657彩票网 北京pk10 1.4.DUIXIBAOMIANYIGONGNENGDEYINGXIANG:XIAOSHUGUANFUJIAOGULANJIANJI10g/kg、30g/kg,LIANFU12TIAN,DUIERXIAOJILVBEN(DNCB)YINQIYOUTXIBAOJIEDAODECHIFAXINGPIFUCHAOMINFANYINGYOUMINGXIANZENGQIANGZUOYONG。XIAOSHUGUANWEIGPs200mg/kgHUO400mg/kg,LIANFU10TIAN,DUIHUANLINXIANANYINQIDEE-MEIGUIHUAXINGCHENGLVDEJIANGDIYOUMINGXIANDUIKANGZUOYONG,KESHIQIHUIFUZHIZHENGCHANGSHUIPING,GUANFUGPs50mg/kg,LIANFU10TIAN,DUIZHENGCHANGXIAOSHUE-MEIGUIHUAXINGCHENGLVCHENGSHUANGXIANGDIAOJIEZUOYONG。HELIU(ROULIU180)XIAOSHUGUANFUGPg100mg/kg,LIANFU12TIAN,DISAIMISONGYOUFATUYIGONGNENGDIXIADASHUGUANFUGPs150mg/kgHUO300mg/kg,LIANFU15TIAN,DUISRBCMIANYIDEPIXIBAOZHONGTEYIMEIGUIHUAXINGCHENGXIBAODEJIANSHAOYOUMINGXIANDEBAOHUZUOYONG。α-BANRUTANGZAOCHENGDEYAJIXINGSHUAILAOMOXINGXIAOSHUGUANFU3%JIAOGULANJINGAOHUNXUANYE0.5ml/SHU,LIANFU50TIAN,KESHIWAIZHOUXUEJIANGDIDELINBAXIBAOα-CUSUANNAIZHIMEI(ANAE)YANGXINGLVXIANZHUTIGAO,YESHIJIANXIAODEDNCBSUOZHIPIFUCHIFAXINGCHAOMINFANYINGMINGXIANZENGQIANG。DANXIAOSHUGUANFUGPs300mg/kgLIANFU7TIAN,DUIXINJIYIZHIPAIYIFANYINGWEIJIANMINGXIANYINGXIANG。YINGYONGMcAb-A-EMEIGUIHUASHIYAN(ZHIJIEFA),DUIFENGSHIXINGXINZANGBINGJIXIANYAOXINGXINZANGBINGTIWAIXUNHUANSHOUSHUBINGRENDEWAIZHOUXUEDANGEHEXIBAOJINXINGYANJIU,JIEGUOBIAOMING,YINGJI(MAZUI、SHOUSHU、TIWAIXUNHUAN)SHI,TXIBAOJIQIYAQUNCD3+、CD4+XIBAOJIANGDI,ERCD8+XIBAOZENGGAO,B+XIBAOYEJIANGDI,CHAYIJIXIANZHU。ZAITIWAIJINGGPsZUOYONGHOU,JIANGDIDECD3+、CD4+XIBAOJIB+XIBAOJUNXIANZHUSHENGGAO,ERSHENGGAODECD8+XIBAOZEMINGXIANJIANGDI,TISHIGP8JUYOUKANGYINGJIZUOYONG,DUIYINGJISHIJITIDEMIANYIYIZHIYOUDIAOJIEZUOYONG。

1.5.DUIZIRANSHASHANGXIBAO(NK)DEYINGXIANG:GPs100μg/ml、200μg/mlSHIDUIRENWAIZHOUXUENKXIBAOHUOXINGYOUJIAQIANGZUOYONG,DAN400μg/mlSHIZEFANYOUYIZHIZUOYONG。XIAOSHUGUANWEIGPs400mg/kg,LIANFU12TIAN,DUIHUANLINXIANANSUOZHIPINKXIBAOHUOXINGJIANGDIYOUXIANZHUJIEKANGZUOYONG。

657彩票网 北京pk10 2.KANGZHONGLIUZUOYONG:2.1.XIAOSHUGUANFUGPs50mg/kg,LIANFU7TIAN,DUIXIAOSHUROULIU(S180)KEYIZHILIUDAXIAO40%。XIAOSHUGUANFUJIAOGULANJIANJI1g/kg、2g/kg,LIANFU10-12TIAN,DUIS180ZUZHIYUNJIANGJIEZHONGYUXIAOSHUYOUYEXIADEZHONGLIUSHENGCHANGYOUMINGXIANYIZHIZUOYONG,YIZHILVFENBIEDA28.9%HE38.1%;DUIS180CHAKUAIYIZHIDEZHONGLIUSHENGCHANG,YIZHIZUOYONGJIAORUO,7.5g/kgSHICAIYOUMINGXIANYIZHIZUOYONG。DUIFUQIANGJIEZHONGBAIXUEBINGL615LIUZHUXIAOSHU,GUANFU2g/kg,LIANFU7TIAN,DUIYUNJIANGFAJIEZHONGZHESHENGMINGYANCHANGLVWEI37.4%(P<0.05),DUICHAKUAIFAJIEZHONGZHESHENGMINGYANCHANGLVKEDA66.6%(P<0.01),ZENGJIAJILIANGZHI7.5g/kgSHI,SHENGMINGYANCHANGLVBUJINBUZENGJIA,FANERJIANXIAOZHI29.6%。GUANFUJIANJI1-2g/kg,DUIXIAOSHUYIZHIXINGGANAIWUMINGXIANYIZHIZUOYONG。FUQIANGJIEZHONGS180XIAOSHUGUANWEIGPs3mg/SHU,LIANFU7TIAN,KESHIMEI1mlFUSHUIZHONGLIUXIBAOSHUMINGXIANDIYUDUIZHAOZU,CHUYUFENLIEZHONGDEXIBAOYEMINGXIANJIANSHAO,GEIYAOZUCHUYUDNAHECHENGQIANQI(G1QI)XIBAODEBAIFENLVMINGXIANGAOYUDUIZHAOZU,ERCHUYUDNAHECHENGHOUQI(SQI)XIBAOBAIFENLVZEMINGXIANDIYUDUIZHAOZU。TISHIGPsKEMINGXIANYIZHILIUXIBAODNAHECHENG。GPsDUIS180XIAOSHUKEMINGXIANZENGJIAPIZANGXISHU,DANDUIXIONGXIANXISHUWUMINGXIANYINGXIANG,WAIZHOUXUEZHONGXIBAOZONGSHU、THXIBAO、BXIBAOZONGSHU、IgM、IgGJUNMINGXIANGAOYUDUIZHAOZU。TISHIGPsBUJINNENGTIGAOXIBAOMIANYIGONGNENG,YEZENGQIANGTIYEMIANYI。

2.2.GPsDEKANGZHONGLIUZUOYONGXUYAOQIADANGDEJILIANG,RUXIAOSHUGUANFUGPs10TIAN,30mg/kgSHI,DUIS180YILIULVDA87.1%,300mg/kgSHIYILIULVZHIYOU61.1%,600mg/kgSHIYILIULVJIN21.1%。ZAITIWAI,GPsYUS180XIBAOGONGTONGFUYU5XIAOSHI,QUCHUYONGYIHONGRANSE(RANCHENGHONGSEZHEWEISIWANGXIBAO),GPsNONGDUWEI0.38%SHI,CHIRANLV54%;NONGDUWEI0.55%SHI,CHIRANLVWEI82.7%;NONGDUWEI0.75%SHI,CHIRANLVWEI87.5%。TISHIGPsDUIS180XIBAOYEYOUZHIJIESHAMIEZUOYONG。AISHIFUSHUIAIXIAOSHUFENBIEGUANFUJIAOGULANDISHANGBUFENJIANJI(NGP 1g/ml)HEXINXIANJIAOGULANYUSHANGZUZHIJIASHUIDAOSUIHOUGUOLV(FGP,1g/ml)0.3ml/SHU,FUSHUIXINGGUANFU15TIAN,SHITIXINGGUANFU30TIAN,DUIFUSHUIXINGXIAOSHU,NGPHEFGPKESHIQISHENGMINGYANCHANGLVFENBIEDA40.7%HE46.6%;DUISHITIXINGXIAOSHUDEYILIULVFENBIEDA33.1%HE36.2%。HELIU(AISHIFUSHUIAI)XIAOSHUWAIZHOUXUESUANXINGCUSUANSUZHIMEI(ANAE)YANGXINGXIBAOLV,DUIZHIWUXUENINGSU(PHA)DEFEITEYIXINGZHUANHUALVJUNBIZHENGCHANGXIAOSHUDI,FUSHANGSHUJILIANGFGAHUONGPQIAOXIAOSHUZEMINGXIANSHENGGAOSHANGSHULIANGXIANGZHIBIAO,YINGYONG5-FUNIAOMIDINGHUOHUANLINXIANANDEAISHIAIXIAOSHU,PILINBAXIBAOZHONGANAEYANGXINGLV,DUIPHADEFEITEYIXINGZHUANHUAYIJINKXIBAODUIAISHIAIXIBAODEDUXINGJUNJIANGDI,ERFUYONGFGPHUONGPDEXIAOSHU,DUISHANGSHUSANXIANGZHIBIAOJUNXIANZHUSHENGGAO。

2.3.JIAOGULANSHUIJIANCHUNCHENTIQUWU5mg(SHENGYAO)/mlKESHIPEIYANGDERENTIGANAIXIBAOZHUSMMC-7721XIBAOBIANYUAN,BAOMOBIANHOU,QIETUOLUOCHENGXUANFUZHUANG。CAIYONGERYIJIYAXIAOAN(DEN)ZHIDASHUGANAIQIANBINGBIANDEMOXING,RUSIYIHANGPsSILIAO(SILIAOZHONGGPsNONGDU1.5g/kgHUO0.48g/kg)GONGFU14TIAN,DUIDENZHIGANAIDEFASHENGYOUYIZHIZUOYONG。GPsZAITIWAI1-10μg/mlSHIDUIFEIAIXIBAOZHUA549、Calu1、592/9DEYIZHIZUOYONGMINGXIANQIANGYUGONGJINGAIHela S3JIJIECHANGXIANAIColo205,ERTONGYANGNONGDUGPsDUIZHENGCHANGRENHUNHELINBAXIBAOBUDANWUYIZHIZUOYONG,QUEYOUCUJINXIBAOZENGZHIDEZUOYONG。JIAOGULANTIQUYE[1.0g(SHENGYAO)/mlHANZAODAI6.44mg/ml,DUOTANG10.697mg/ml]ZAI1-20μl/mlSHI,DUIRENDACHANGAIXIBAO(Hce8693)DEDNAHECHENGYOUYIZHIZUOYONG,QIEYUJILIANGXIANGGUAN,DANZAIJIAOGAONONGDUSHI,DUIZHENGCHANGCHENGXIANWEIXIBAOYIYOUYIZHIZUOYONG,NONGDUDIYU10μl/mlSHI,DUIDACHANGAIXIBAOYOUYIZHIZUOYONG,DUIZHENGCHANGCHENGXIANWEIXIBAOWUBULIANGYINGXIANG。FANSHIZAIDAMAWANXINGGUJIASHANGDEC20HUOC21SHANGYOUYOULIQIANJIDEZAODAI,DUIPEIYANGDEFEIAI、ZIGONGAI、HEISESUZHONGLIUXIBAOJUNYOUYIZHIXIAOGUO,ERDUIZHENGCHANGXIBAODEZENGZHIZEWUBULIANGYINGXIANG。

657彩票网 北京pk10 3.YANHUANSHUAILAOZUOYONG:JIAOGULANNENGMINGXIANYANCHANGXIBAOPEIYANGDECHUANDAIDAISHU。YIRENPIFUXIBAOZUOTIWAIPEIYANG,JIAGPs200μg/mlDEPEIYANGYEKESHIXIBAOCHUANZHI27DAI,ERDUIZHAOZUJINNENGCHUANZHI22DAI。YIRENTAIFEIERBEITIXIANWEIXIBAOCHUANDAIPEIYANGYEHUOLEISIJIEGUO,DUIZHAOZUCHUANZHI51DAI,GPsZUKECHUANZHI59DAI。0.5%HE1.0%JIAOGULANJINGAOSHUIRONGYEGEIYUHUAJIAYINGYINYONG,KESHICIXIONGJIAYINGBANSHUCUNHUOSHIJIAN、PINGJUNSHOUMINGHEZUIGAOSHOUMINGJUNYOUYANCHANGZUOYONG,1%JIAOGULANZUHUANNENGSHIJIAYINGNAONEICHAOYANGHUAWUQIHUAMEI(SOD)HUOXINGXIANZHUSHENGGAO,BINGERQUAN(MDA)HANLIANGXIANZHUJIANGDI。HAN0.5%HE1%JIAOGULANJINGAODEGUOYINGPEIYANGJIDUIXIONGGUOYINGPINGJUNSHOUMINGFENBIEYANCHANG11.8%HE12.2%;0.25%NONGDUDUICIXIONGYINGPINGJUNSHOUMINGFENBIEYANCHANG18.5%JI24.1%。0.5%JIAOGULANJINGAOZAIFUYUQIDELUANKAISHIGEIYAO,QIPINGJUNSHOUMINGBICHENGCHONG(30dLING)KAISHIGEIYAOYOUMINGXIANYANCHANG,YANCHANGBAIFENLVQIANZHEWEI53.3%(XIONGXING)、46.1%(CIXING),HOUZHEWEI14.4%(XIONGXING)9.7%(CIXING),JIAOGULANTIQUWUNENGCUJINGUOYINGYOUCHONGDESHENGCHANGFAYU,DANDUIGUOYINGDEXINGHUOLIWEIJIANYINGXIANG。5YUELINGXIAOSHUCAIYONGHANJIAOGULANJIANJISILIAO(2.5gJICHUSILIAOHAN0.1gSHENGYAO)SIYANG4GEYUE,CUNHUO50%, DUIZHAOZUCUNHUO0%,WEISI2GEYUEJIKETIGAOXIAOSHUSODHUOXING。d-BANRUTANGYOUFADEXIAOSHUYAJIXINGSHUAILAOMOXING,RUTONGSHIMEIRIFUQIANGZHUSHEJIAOGULANJINGAOHUNXUANYE15mg/SHU,GONG40TIAN,KEXIANZHUDUIKANGSHUAILAOMOXINGXIAOSHUXUEXIZHUDONGTAOBIFANYINGNENGLIDEXIAJIANG、NAONEIDANANYANGHUAMEI(MAO-B)HUOLIDEYICHANGSHENGGAOJINAOZHIHEZHIDEZENGJI,SHISHUAILAOMOXINGXIAOSHUWEISUODEXIONGXIANHUIFUDAOZHENGCHANGSHUIPING,ZENGDADEPIZANGYEHUIFUDAOZHENGCHANGSHUIPING。YOUXIAOSHUWEISHIHANJIAOGULANSHUITIWUGANJINGAOSILIAO200mg/kg,GONG3GEYUE,KESHINAO、XINZUZHIZHONGZHIHEZHIHANLIANGJIANSHAO,GANZANGZHONGZHIHEZHIHANLIANGSUIYUDUIZHAOZUWUXIANZHUCHAYI,DANYEBIDUIZHAOZUDI。LAONIANDASHUWEISIHAN0.5%HE0.25%JIAOGULANSHUITIWUGANJINGAO2.5GEYUE,DUIXIN、GAN、NAOZUZHIGUOYANGHUAZHIZHI(LPO)YOUMINGXIANJIANGDIZUOYONG,0.5%NONGDUZUDUIXUEQINGHEGANZANGZONGDANGUCHUN、SANXIANGANYOUDOUYOUMINGXIANJIANGDIZUOYONG。ZAITIWAI,250μg/1.5mlHE500μg/1.5mlNONGDUSHIDUIDASHUXIN、NAO、GANZUZHILPOHANLIANGJUNYOUXIANZHUJIANGDIZUOYONG。XIAOSHUGUANFUGPs80mg/kg,2GEYUE,XUEJIANG、GANHENAOZHONGLPOHANLIANGJUNXIANZHUJIANGDI,QIEKETIGAOGANHENAOZHONGSODHUOXING,YIKEJIANGDIXIAOSHUPIFUQIANFUANSUANHANLIANG,TISHIGPsYOUKANGYANGHUAHEYANHUANSHUAILAOZUOYONG。

4.DUIZHIZHIDAIXIEDEYINGXIANG:4.1.SHEQUGAOTANGGAOZHISILIAOYOUFAGAOZHIXUEZHENGDASHU,XUEQINGZHONGXINGZHIFANGXIANZHUSHENGGAO,XUEZHONGLPOSHANGSHENG,RUFUGPs500mg/kg、100mg/kg(HUNYUSILIAOZHONGFUYONG)7XINGQI,ZEXUEQINGZHONGXINGZHIFANG、ZONGDANGUCHUNSHUIPINGXIANZHUXIAJIANG,GANZHONGLPODESHANGSHENGBEIYIZHI。SHIYANXINGGAOZHIXUEZHENGJIATUGUANFUGPsl00mg/kgGONG4XINGQI,NENGMINGXIANDUIKANGXUEQINGZONGDANGUCHUN(TC)SHENGGAO,DUISANXIANGANYOU(TG)HEGAOMIDUZHIDANBAIDANGUCHUN(HDLc)YINGXIANGSIHUBUDA,HDLYOUKANGDONGMOZHOUYANGYINGHUA(As)YINZIZHICHENG,YOUYUHDLcSUITCSHUIPINGSHENGGAOERZENGJIA,GUYIQIJUEDUIZHILAIBIJIAOYIYIBUDA,MUQIANZHUZHANGYONGAsI(DONGMOZHOUYANGYINGHUAZHISHU)=[(TC-HDLc)/HDLc]HUOHDLc/TCLAIHENGLIANGGETIAsDEYILIXING,JISUANBIAOMING,GPsNENGMINGXIANJIANGDIAsI,TIGAOHDLc/TC,WUYIDUIYUFANGAsYOUJIJIYIYI。AsBANKUAIZHONGDANGUCHUNZHUYAODIMIDUZHIDANBAI(LDL)DAFENZIXINGSHICHENJIYUDONGMOBI,YOUFAGUANBIPINGHUAJIXIBAOZENGSHENG,SUNSHANGXUEGUANNEIPIXIBAO,JISUANBIAOMING,GPsNENGMINGXIANJIANGDILDLSHUIPING,DUIYUFANGAsJUYOULIANGHAOZUOYONG。

4.2.GAOZHIXUEZHENGTUXUEQINGLPOYUXINJIZHIHEZHI(Lf)HANLIANGJUNMINGXIANGAOYUZHENGCHANGTU,GPsNENGMINGXIANJIANGDIXUEQINGLPOHEXINJILf,BIAOMINGGPsHUANJUYOUKANGYANGZIYOUJI、BAOHUXUEGUANNEIMODEZUOYONG。GAOZHIXUEZHENGDASHUGUANFUGPsl00mg/kg、300mg/kgGONG15TIAN,KESHIXUETC、TG、LDLJIANGDI,HDL/LDCBIZHIXIANZHUSHENGGAO。XIAOSHUYIYINSHUIFANGSHIGEIGPs300mg/kgGONG4GEYUE,NENGYIZHIHUO(HE)QINGCHUXINJILfDEXINGCHENG。FUQIANGZHUSHEXIANDANHUANGRUYEYINQIDEGAOZHIXUEZHENGXIAOSHU,GUANFUGPs200mg/kg7TIAN, KEMINGXIANJIANGDIXUETCNONGDU;GAOZHISILIAOCHANSHENGDEGAOZHIXUEZHENGDASHU,GUANFUGPs200mg/kg7TIAN,NENGXIANZHUJIANGDITC、LDLHEJIDIMIDUZHIDANBAI(VLDL)HANLIANG,SHENGGAOHDLHEHDL/LDLBIZHI。

657彩票网 北京pk10 4.3.GAOZHIXUEZHENGHUANZHEFUYONGGPsYIKEJIANGDIXUETC、TG、LDLc。LINGYOUBAODAOGAOZHIXUEZHENGHUANZHEFUGPs40mg,MEIRI3CI,GONG30TIAN,NENGMINGXIANJIANGDIXUEQINGZAIZHIDANBAI(apoB100)JIZHIDANBAI(LP(a)DEHANLIANG,RENWEIDUITIGAOQUANSHENZUZHIDEGONGXUE,FANGZHIDONGMOZHOUYANGYINGHUAYOUZHONGYAOYIYI,ERDUIXUEQINGHDLc、LDLc、VLDLcJITC、TGDEHANLIANGWUMINGXIANYINGXIANG。XIAOSHUZIYOUYINYONGJIAOGULANCHUNTIWU13TIAN,BUJINNENGTIGAOGANZANGSODHUOLI,TONGSHIYEZENGQIANGLESODNAIRE、NAISUANXINGNENG,QILEBAOHUSODDEZUOYONG。ZAITIWAI,GPsDUILAONIANDASHUGANYUNJIANGLPOSHENGCHENGYOUMINGXIANYIZHIZUOYONG,DASHUGUANWEIGPs0.25g/kg 8TIAN,ZHIYUCHOUYANGJUZHONG(CHOUYANGSUNSHANGDEZIYOUJIMOXING)BINGJIXUGEIYAO10TIAN,KESHIGANZANGHEXUEJIANGLPOHANLIANGMINGXIANDIYUDUIZHAO,HONGXIBAOSODHUOLIYEMINGXIANGAOYUDUIZHAOZU。LAONIANDASHU(26GEYUELING)YINSHUIFUYONGGPs 0.05g/kg 80TIAN,YENENGMINGXIANJIANGDIGANZANGLPOHANLIANG,ZENGQIANGHONGXIBAOSODHUOLI。

657彩票网 北京pk10 4.4.ZAITIWAI,GPs 2.5-160μg/mlSHI,DUIFe2+ -BANGUANGANSUAN、WEISHENGSU C-NADPHHESILVHUATANYOUFADEDASHUGANWEILITIMDASHENGCHENGYIJIZIFAXINGMDASHENGCHENGJUNYOUYIZHIZUOYONG,QIECHENGLIANGXIAOGUANXI。ANDENGJILIANGBIJIAO,GPsDELIAOXIAOMINGXIANGAOYURENCANZONGZAODAI。Fe2+ -BANGUANGANSUANYINQIDESUNSHANGSHIDASHUGANWEILITI、XIANLITIMOWEIZHANDUMINGXIANZENGDA,BIAOSHIMOLIUDONGXINGJIANGDI,RUTONGSHIJIARU GPs2.5-160μg/mlKEDUIKANGQIMOLIUDONGXINGDEXIAJIANG,DANDUIWEISHOUSUNSHANGDEZHENGCHANGGANWEILITI、XIANLITIMOLIUDONGXINGWUYINGXIANG。YONGHUANGPIAOLING-HUANGPIAOLINGYANGHUAMEI(X-XOD)XITONGYOUFATUNSHUXINRUTOUJIYANGZIYOUJISUNSHANG,ZAIX-XODZUOYONGXIA,RUTOUJISHOUSUOLIXIANSHENGGAOHOUJIANGDI,GONGNENGBUYINGQISUODUAN,XINGFENXINGTIGAO,SHENSHANGXIANSUYOUFADEZILVXINGZENGJIA,XINJIZHONGSODHUOXINGJIANGDI,ERMDAHANLIANGSHENGGAO。RUXIANGEIGPs50μg/ml,ZAIGEIX-XOD,ZERUTOUJISHOUSUOGAOFENGTUICHI,BINGYIZHIQIFUXINGJILIZUOYONG,TONGSHI,NIZHUANX-XODSUOZHIDERUTOUJIBUYINGQI、XINGFENXINGYUZILVXINGDEGAIBIAN,XINJIZUZHIZHONGMDAHANLIANGDEYIHUIFU。TISHIGPsDUITUNSHUXINJIDEYANGHUASUNSHANGYOUBAOHUZUOYONG。DIANJIEKrebYECHANSHENGYANGZIYOUJI(OFR),KESHIYIXIANDANJIAN(Ach)YOUFADETUZHUDONGMOXUEGUANHUANSHUZHANGBAIFENLVMINGXIANJIANDI,GPs25μg/ml、50μg/ml、100μg/mlJUNKEBAOHUXUEGUANNEIPIMIANSHOUOFRSUNSHANG,GPs50μg/mlDEZUOYONGNENGBEIYINDUOMEIXIN(INDO)ZUDUAN,X-XODYESHIXUEGUANHUANSHUZHANGGONGNENGJIANGDI,GPs50μg/mlKEDUIKANGX-XODDESUNSHANGZUOYONG。MEILAN(Mb)YEKESUNSHANGXUEGUANHUANSHUZHANGGONGNENG。GPs100μg/mlYENENGDUIKANGMbDEZUOYONG。XUEGUANNEIPINENGSHIFANGQIANLIEHUANSU(PGI2)HENEIPIYANSHENGSONGCHIYINZI(EDRF)DENGDIAOJIEXUEGUANZHANGLIHEZENGQIANGZISHENKANGSUNSHANGNENGLI。

657彩票网 北京pk10 4.5.OFRSUOZHIXUEGUANSHUZHANGNENGLIJIANGDIYUNEIPISHIFANGEDRFJIANSHAOYOUGUAN,GPsNENGDUIKANGYINMbYIZHIEDRFSUOZHIXUEGUANSHUZHANGGONGNENGJIANGDI,TISHIGPsKENENGBAOHUEDRFHUOXING。GPsDEZUOYONGKEBEIINDOZUDUAN,JIANJIEBIAOMINGGPsZUOYONGKENENGTONGGUOCUJINZUZHISHIFANGPGI2JINERKANGMOZHIZHIGUOYANGHUAYOUGUAN。

657彩票网 北京pk10 4.6.GPsKEJIANSHAORENZHONGXINGBAIXIBAONEICHAOYANGYINLIZIHEGUOYANGHUAQINGHANLIANG;DUIRENDANHEXIBAOHESHUJUSHIXIBAO,GPsKEJIANSHAOJIAOMUDUOTANGCHUFADEHUAXUEFAGUANGXINGYANGHUABAOFA;DUIYUFe2+ -BANGUANGANSUAN、KANGHUAIXUESUAN-NADPHHUOGUOYANGHUAQINGZAIGANWEILITIHEXUEGUANNEIPIXIBAOCHANSHENGDELPOZENGJIA,GPsKEYIZHIZHEYIZUOYONG,YOUYUYANGHUASUNSHANGERJIANSHAOLEDEGANWEILITIHEXIANLITIDEMOLIUDONGXING,GPsKENIZHUAN,ZENGJIAXUEGUANNEIPIXIBAOXIANLITIMEIHUOXING,JIANSHAOZHEXIEXIBAONEIRUSUANTUOQINGMEIDEXIELOU,TISHIGPsKEBAOHUSHENGWUMOMIANSHOUYANGHUASUNSHANG,GPsDEZHEXIEGUANGFANDEKANGYANGHUAXIAOGUODUIDUOZHONGJIBINGRUDONGMOZHOUYANGYINGHUA、GANBINGHEYANZHENGDEYUFANGHEZHILIAOJUNKEYOUYIDINGJIAZHI。YOURENZHICHUZHIZHIGUOYANGHUAZUOYONGKESHIZHIZHIHANLIANGJIAOGAODESHENGWUMOZUCHENGFASHENGBIANHUA,QIESHIDNA、RNAJIEGOUSHOUDAOSUNHAI,YINQIDANBAIZHIFENZIDEJIAOLIAN,DAOZHIXIBAODESHUAILAO,YINERLPOYULAONIANXIANGGUANYICHENGWEIYINRENZHUMUDEWENTI,JIAOGULANXIANZHUJIANGDILPODEZUOYONGZHIDEZHONGSHI,QIJIZHIZEYOUDAICHANMING。

4.7.JIAOGULANNENGYIZHIZHIFANGXIBAOCHANSHENGYOULIZHIFANGSUANJIHECHENGZHONGXINGZHIFANG。YONGDASHUFUGAODEZHIFANGZUZHIZHIBEIZHIFANGXIBAOJINXINGPEIYANG,ZAIPEIYANGYEZHONGJIARUACTHHUOSHENSHANGXIANSUKESHIZHIFANGXIBAOFENJIEERCHANSHENGYOULIZHIFANGSUAN,RUTONGSHITIANJIAGPsZEJIANSHAOYOULIZHIFANGSUANDESHENGCHENGLIANGDA28%ZUOYOU。YIZHIFANGXIBAOHESHIZONGHUAHEWU14C-PUTAOTANGZAI37℃GONGTONGPEIYU30FENZHONG,CEDINGZHIFANGXIBAODEMEIFENZHONGMOCHONGSHU(CPM)ZUOWEIPUTAOTANGJINRUXIBAOHECHENGWEIZHONGXINGZHIFANGDEZHIBIAO,PEIYANGYETIANJIAGPsHOU,MEIKEZHIFANGXIBAOCEDEDECPMSHUJINWEIWEIJIAGPsZUDE50%ZUOYOU。TISHIJIAOGULANYOUKENENGCHENGWEIXINDEZHIZHIDAIXIEDIAOJIEYAOWU。

657彩票网 北京pk10 5.DUIXINXUEGUANXITONGDEZUOYONG:5.1.GPsDINONGDUDUILITIWAXINYOUXINGFENZUOYONG,2.4mg/mlSHIZUOYONGZUIQIANG,4mg/mlSHIZECHENGYIZHIZUOYONG。MAZUITUJINGZHUGPs8mg/kg,KESHIXUEYAMINGXIANSHENGGAO,16mg/kgSHIZESHIXUEYAMINGXIANJIANGDI,QIEDUICHUITIHOUXIESUDAOZHIDEXINJIQUEXUE(TBOGAOSONGJIS-TDUANXIAYI)YOUMINGXIANDUIKANGZUOYONG。MAZUIKAIXIONGQUANJINGZHUGPs5mg/kgHUO10mg/kg,NENGMINGXIANJIANGDIQUANXUEYAHEZONGWAIZHOUZULI、NAOXUEGUANYUGUANZHUANGXUEGUANZULI,ZENGJIAGUANMOLIULIANG,JIANMANXINLV,SHIXINZANGZHANGLI-SHIJIANZHISHUXIAJIANG(JIANJIEFANYINGXINJIYANGHAOLIANGJIANGDI),DUIXINJISHOUSUOXINGNENGHEXINZANGBENGXUEGONGNENGWUMINGXIANYINGXIANG,BIDENGLIANGRENCANZONGZAODAIDEZUOYONGLVEQIANG。JINGZHUGPs1mg/kgZEKETIGAOSHOUSUOYAJISHUZHANGYA,MINGXIANTIGAOXINJIDESHOUSUOJISHUZHANGXINGNENG,ZENGQIANGXINJISHOUSUOLI。ZAIZUOSHISHOUSUOSUDUJIAKUAIDETONGSHI,WAIZHOUZULIBINGBUZENGJIA,CONGERTIGAOLEXINZANGDEMEIFENSHUCHULIANG。TISHIGPsDUIDASHUXINJIQUEXUEZAIGUANZHUSUNSHANGYOUBAOHUZUOYONG,ZUOYONGJIZHIYUKANGYANGHUAZUOYONGYOUGUAN。LITIDASHUXINZANGGUANLIU,TINGGUAN30FENZHONG,ZAIGUAN20FENZHONG,GPs3Oμg/mlHE50μg/mlKEXIANZHUJIANGDIBUKENISHIZHANFASHENGLV,50μg/mlSHIKEXIANZHUYIZHIXINJIRUSUANTUOQINGMEI(LDH)SHIFANG。GPsHUANKEXIANZHUTIGAOQUEXUEZAIGUANXINJISODHUOXING,MINGXIANJIANGDIMDASHUIPING,DUIXINJIQUEXUEZAIGUANSUNSHANGJUBAOHUZUOYONG。JIEZHAGUANMOYINQIJIXINGXINJIGENGSIDASHU,YUJIEZHAQIAN30FENZHONGJIJIEZHAHOULIJIFUQIANGZHUSHEGPs25mg/kg,KESHIQUEXUE24XIAOSHIDEXINJIGENGSIFANWEIXIANZHUSUOXIAO,BINGSHIQUEXUE6XIAOSHIJI10XIAOSHIDASHUXUEQINGLINSUANJISUANJIMEI(CPK)HERUSUANTUOQINGMEI(LDH)MINGXIANJIANGDI,SHIQUEXUEHOU30FENZHONGSHIQUEXUEBIANYUANQUXINJICHAOWEIJIEGOUSUNSHANGMINGXIANJIANQING。

5.2.ZAITIWAI,GPs50μg/ml、100μg/mlJI200μg/mlNENGJIANQINGDASHUPEIYANGXINJIXIBAOQUETANGQUEYANGXINGSUNSHANG,YIZHIQUEYANGQUETANG6XIAOSHIXINJIXIBAOCPKHELDHDESHIFANG。MAZUIDASHUJINGZHUGPs10mg/kgHUO25mg/kg,30FENGONGNEIDUIXINLV、XUEYA、ZUOSHISHOUSUOYAHESHUZHANGYA、ZUOSHIYALIBIANHUAZUIDAZHI、XINZHISHUDENGXUELIUDONGLIXUEZHIBIAOJUNWUMINGXIANBIANHUA。JIEZHAZUOGUANMOCHANSHENGXINJIGENGSIDEJIATU,SHUQIAN30FENZHONGFUQIANGZHUSHEGPs100mg/kgKEJIANGDI∑ST(XIONGDAOLIANXINDIANTUSTDUANTAIGAOZONGHAOFUSHU)HENST(STDUANSHENGGAODEXINDIANTUSHU),TONGJIXUEWUXIANZHUCHAYI,ERRENCANZONGZAODAI(GS)50mg/kgJIYOUXIANZHUJIANGDIZUOYONG;GPs100mg/kgNENGXIANZHUJIANGDIGENGSIHOUXUEQINGYOULIZHIFANGSUAN(FFA)DESHENGGAO,XIANZHUSUOXIAOXINJIGENGSIFANWEI,DANBIGSZUOYONGRUO。JIEZHAGUANMOZUOSHIZHICHANSHENGXINJIGENGSIDEDASHU,SHUQIANFUQIANGZHUSHE100mg/kg,GPsHEFGNG(FEIRENCANZAODAIBUFEN)JUNNENGMINGXIANYIZHIGENGSIHOUXINJIMDADESHENGGAO(P<0.01),FGNGHUANNENGSHIGENGSIHOUJIANGDIDESODHUOXINGMINGXIANSHENGGAO,GPsHEGsYEYOUSHISODHUOXINGSHENGGAODEQUSHI,GENGSIYINQIDEXINJICPKHUOXINGJIANGDI,GSSHIZHIMINGXIANSHENGGAO,GPsHEGSYEKESHIZHISHENGGAO,DANZAITONGJIXUESHANGJIEJINXIANZHUXING。GPsDUIJIATUNEIDUSUXIUKEHUANYOUMINGXIANKANGXIUKEHEYUFANGJIFAXINGMISANXINGXUEGUANNEININGXUE(DIC)。FUQIANGZHUSHEGPs40mg/kg,KEMINGXIANYANCHANGLIDUOKAYINZHONGDUXIAOSHUCUNHUOSHIJIAN,DASHUFUQIANGZHUSHEGPs80mg/kgKEMINGXIANZENGJIADUILIDUOKAYINDENAISHOULIANG。ZAITIWAI,GPs2μg/mlNENGMINGXIANYANCHANGLITITUNSHUXINFANGGONGNENGXINGBUYINGQI(FRP),0.01-1μg/mlSHIKENONGDUYILAIXINGJIANGDILITITUNSHUYOUXINFANGZILVXING,DUIXINFANGJISHOUSUOXINGWUMINGXIANYINGXIANG。MAZUIMAOJINGZHUGPs50mg/kg,XUEYAXIAJIANG40.7%,WEICHI30FENZHONGYISHANG,XINLVWUBIANHUA,MOYACHAZENGDA,YANSUANPUNAILUOER(XINDEAN)BUZUDUANQIJIANGYAZUOYONG。

6.DUIXUENINGHEXUEXIAOBANJUJIDEYINGXIANG:6.1.ZAITIWAI,GPs0.25-1.00mg/mlSHIDUIHUASHENGSIXISUAN(AA)YOUDAODETUXUEXIAOBANJUJIYOUCUJINXUEXIAOBANJIEJUZUOYONG,DUIJIAOYUANYOUDAODEXUEXIAOBANJUJI,KESHIJUJIQUXIANDEPODUZHUJIANBIANXIAO,QIANFUQIZHUJIANYANCHANG,SHUOMINGKEJIANMANXUEXIAOBANJUJIDESUDU。JIATUJINGZHUGPs40mg/kg,DUIADP、AAHEJIAOYUANYOUDAODEXUEXIAOBANJUJIYOUMINGXIANYIZHIZUOYONG,CHIXUYUE60FENZHONG,5FENZHONGSHIYIZHIZUOYONGZUIQIANG。ZAITIWAI,GPsZAIYIZHIXUEXIAOBANJUJIDENONGDUSHI,NENGMINGXIANYIZHIJIAOYUANYOUDAODEXUEXIAOBAN5-QIANSEAN(5-HT)DESHIFANG,BINGNENGSHENGGAOXUEXIAOBANXUANYEZHONGcAMPSHUIPING,QIEXIAOYINGYUJILIANGXIANGGUAN。DASHUPIXIAZHUSHEGPs50mg/kg,DUIXUEXIAOBANXUESHUAN(DONGMOXUESHUAN,ZHUYAOYOUXUEXIAOBANJIHUOSUOZHI)HEJINGMOXUESHUAN(ZHUYAOSHININGXUEXITONGJIHUOSUOZHI)JUNYOUYIZHIZUOYONG。

657彩票网 北京pk10 6.2.ZAITIWAI,GPs 0.25-1.00mg/mlDUIXUEXIAOBANZHONGXUESHUANWANB2(TXB2)HEZHUDONGMOZHONG-6-TONG-QIANLIEXIANSUF1α.(6-keto-PGF1α)DESHENGCHENGJUNYOUYIZHIZUOYONG。IC50FENBIEWEI1.03mg/mlHE1.15mg/ml,BIAOMINGGPsKEYIZHIAADAIXIE,KENENGSHIYIZHIXUEXIAOBANJUJIHESHIYANXINGXUESHUANXINGCHENGDEJIZHIZHIYI。ZAITIWAI,JIAOGULANSHUIJIANCHUNCHENTIQUWU0.25-2g/LMINGXIANYIZHIAAYOUDAODETUXUEXIAOBANJUJIHETXB2SHIFANG,YIZHITXB2SHIFANGDEIC50WEI0.28mg/ml。TUJINGZHUTIQUWU35mg/kgHOU10FENZHONGHE20FENZHONGSHI,AAYOUDAODEXUEXIAOBANJUJIMINGXIANYIZHI,10-40FENZHONGQIJIAN,XUEXIAOBANSHIFANGLIANGTXB2MINGXIANJIANSHAO。0.25-4mg/mlZAITIWAIDUITUXIONGZHUDONGMOSHIFANG6-keto-PGF1αWUYINGXIANG,BIAOMINGTIQUWUDUIJIANGDITXA2/QIANLIEHUANSUBIZHIYOUJIAOHAOZUOYONG。YONGRENXUEJINXINGDETIWAISHIYANBIAOMING,JIAOGULANJIANJI0.25mg/mlNENGMINGXIANYIZHIADP、FUHEYOUDAOJI(YOUADP、SHENSHANGXIANSUHESUANXINGZHANDUOTANGDENGLIANGZUCHENG)YOUDAODEXUEXIAOBAN1FENZHONGHE5FENZHONGZUIDAJUJILV,BINGCUJINJIEJUFASHENG,HUANDUITIWAIXUESHUANXINGCHENGJUYOUXIANZHUYIZHIZUOYONG。JIANJIYUPINXUEXIAOBANXUEJIANGHUNHEHOU,SHANGNENGYIZHIDUOZHONGNINGXUEYINZIHUOXING,SHIBAITAOTUBUFENNINGXUEHUOMEISHIJIAN(KPTT)、NINGXUEMEIYUANSHIJIAN(PT)、NINGXUEMEISHIJIAN(TT)、QISHEDUSHIJIAN(AT)、KUISHEDUFUGAISHIJIAN(RVV-RT)、KUISHEDULINZHISHIJIAN(RVV-CT)DENGNINGXUESHIYANSHIJIANYANCHANG。CIWAI,BINGYOUJIASUHONGXIBAODIANYONGSUDUDEZUOYONG。BIAOMINGGAIYAOSHIYIZHONGJUYOUYIZHIXUEXIAOBANGONGNENG、NINGXUEGONGNENGJIHONGXIBAOJUJIXINGDENGDUOGEHUANJIEDEKANGXUESHUANXINGCHENGYAOWU。KUISHEDUNENGJIHUOXYINZIYINQININGXUE,RVV-CTCEDINGXUYAOWAIYUANXINGLINZHICUNZAI,RVV-CTCEDINGZEYILAIHUANZHEZISHENXUEXIAOBANSHANGXUEXIAOBANYINZI(PE3)DEHUOLI,BENPINDUIRVV-RTDEYANCHANGMINGXIANCHAOGUODUIRVV-CTDEZUOYONG,FANYINGGAIYAOSHANGNENGYIZHIPF3HUOXING。XIAOSHUGUANFUGPs250mg/kg、500mg/kg,LIANFU6TIAN,DUIHUANLINXIANANCHANSHENGDEBAIXIBAOJIANSHAOYOUFEICHANGXIANZHUDESHENGGAOZUOYONG。DUI60GUZHAOSHEXIAOSHUYIYOUSHENGGAOBAIXIBAOZUOYONG,DANDUIZHENGCHANGXIAOSHUBAIXIBAOSHUZEWUMINGXIANYINGXIANG。

657彩票网 北京pk10 7.DUIZHONGSHUSHENJINGXITONGDEZUOYONG:XIAOSHUFUQIANGZHUSHEJIAOGULANTIQUWU100mg/kg、200mg/kg,KEMINGXIANYANCHANGWUBABITUONASHUIMIANSHIJIAN。XIAOSHUGUANFUJIAOGULANJINGAO(HANGPsYUE20%)450mg/kgKEMINGXIANJIANSHAOXIAOSHUDEZIFAHUODONG。BIAOMINGJIAOGULANHUOSUOHANGPsYOUMINGXIANZHENJINGZUOYONG。XIAOSHUGUANFUJINGAO450mg/kg,YONGREBANFAZHENGMINGYOUXIANZHUZHENTONGZUOYONG,DUIZHENGCHANGXIAOSHUTIWENZEYOUDUANSHISHENGGAOZUOYONG,BINGYOUMINGXIANZENGQIANGXIAOSHUCHANGYANAIQUEYANGZUOYONG,XIAOSHUYOUYONGSHIYANYOUXIANZHUKANGPILAOZUOYONG,HUANYOUXIANZHUNAIGAOWENZUOYONG。XIAOSHUGUANFUGPsl50mg/kg,LIANFU3RI,KEMINGXIANYANCHANGYOUYONGSHIJIAN,YINENGMINGXIANYANCHANGXIAOSHUPAGANSHIJIAN,FUQIANGZHUSHEGPs200mg/kgNENGMINGXIANYANCHANGNAIQUEYANGSHIJIAN。DASHUCHANGSHIJIANYOUYONGHOUXUETANGSHUIPINGHEJITANGYUANHANLIANGJUNMINGXIANJIANGDI,GUANFUJIAOGULANTIQUWU200mg/kgGONG14RI,NENGSHICHANGSHIJIANYOUYONGDASHUBAOCHIJIAOGAOXUETANGSHUIPING,JIANSHAOJITANGYUANSUNHAO,ZHEKENENGSHIJIAOGULANKANGPILAODEZHONGYAOYUANYIN。GPsHUANKEJIANSHAOJIZHUMAISIKALINYINQIXIAOSHUHOUZHIDESAONAOSHU,JIANSHAOFUQIANGZHUSHECUSUANYINQIXIAOSHUDENIUTISHU,YIBIAOMINGGPsDEZHENJINGYUZHENTONGZUOYONG。XIAOSHUPIXIAZHUSHEJIAOGULANSANZHONGTIQUWU(SHUI、20%YICHUNHE95%YICHUNTIQUWU)3.0g/kg,LIANXU4-5RI,JUNKEGAISHANZHANGLIUJIANYINQIDEJIYIHUODEZHANGAI;JIAOGULAN20%YICHUNTIQUWUDUIDANBAIHECHENGYIZHIJI(HUANJIXIANYAAN、LVMEISU)ZAOCHENGDEJIYIGONGGUBULIANGYIJI20%YICHUNYINQIDEJIYIZAIXIANZHANGAIJUNYOUJIEKANGZUOYONG。XIAOSHUFUQIANGZHUSHELIXUEPING0.25mg/kgGONG5RI,KESHITIZHONG、TIWEN、ZIFAHUODONGJUNMINGXIANXIAJIANG,BINGYINQILIANXIACHUI、GONGBEIWANQU、FUXIE、TIMAOWUGUANGZEDENG,GUANFUGPs50mg/kg、100mg/kg、200mg/kg,LIANFU10RI,KEMINGXIANGAISHANLIXUEPINGYINQIDETIZHONG、TIWENHEZIFAHUODONGJIANGDI,TONGSHISHIFUXIE、JIANXIACHUI、GONGBEIWANQU、TIMAOWUGUANGZEYOUSUOGAISHAN。GPsKEGAISHANLIXUEPINGDUIZHONGSHUDANANDIZHIDEHAOJIEZUOYONG,DANGPsBENSHENDUIZHENGCHANGXIAOSHUNAONEIDANANDIZHIJIBUFENDAIXIECHANWUYINGXIANGBUMINGXIAN,YEBUYINQIMINGXIANDETIZHENGGAIBIAN。 DASHUNAOQUEXUEZAIGUANLIUSUNSHANGMOXINGDENAOXISHU(NAOZHONG/TIZHONG)GAOYUDUIZHAOZU,RUZAIQUEXUEQIAN15FENZHONGFUQIANGZHUSHEGPsl00mg/kg,ZEKESHINAOXISHU、NAOHANSHUILIANG、NAOZUZHIMDAHANLIANGJUNJIANGDI,BIAOMINGGPsDUIDASHUQUEXUEZAIGUANZHUSUNSHANGYOUMINGXIANBAOHUZUOYONG。JIATUGUANBISHUANGCEJINGZONGDONGMO,TONGSHIDIYADIGUANZAOCHENGJIXINGBUWANQUANXINGNAOQUEXUE,JINGZHUGPs50mg/kgKEMINGXIANGAISHANNAOQUEXUE60FENZHONGHOUNAODIANTUBIANHUA,JIANGDINAOJINGMOXUEZHONGRUSUANTUOQINGMEI(LDH)HELINSUANJISUANJIMEI(CPK)HUOXING,GAISHANQUEXUEHOUNAOZUZHIXINGTAIXUEBIANHUA,TISHIGPsDUINAOQUEXUEYOUBAOHUZUOYONG。

8.QITAZUOYONG:DASHUFUQIANGZHUSHEGPsl0mg/kgGONG10RI。KEFANGZHIDISAIMISONGYINQIDESHENSHANGXIANHEXIONGXIANWEISUOYIJIXUEJIANGPIZHICHUNHANLIANGDEJIANSHAO。XIAOSHUGUANFUGPs70mg/kg、350mg/kg,GONG6RIYIKEFANGZHIDISAIMISONGYINQIDESHENSHANGXIANWEISUO,QIENENGSHISHENGGAODESHENSHANGXIANWEISHENGSUCHANLIANGJIANGDI。TISHIGPsKESHIYONGYUKANGTANGPIZHIJISUFUZUOYONGDEYAOWU。XIAOSHUGUANWEIJIAOGULANTIQUWU20RI,NENGMINGXIANZENGJIAXIONGSHUGAOWAN、JINGNANG、QIANLIEXIANHECISHUZIGUANDEZHONGLIANG,TISHIQIJUYOUXIONGXINGHECIXINGJISUYANGZUOYONG。 DASHUPIXIAZHUSHEGPs50mg/kgGONG6RI,NENGMINGXIANYIZHISILVHUATANYINQIDEXUEQINGBINGANSUANZHUANANMEI(ALT)HUOLIDESHENGGAO,BINGLIQIEPIANXIANSHIGANXIBAOKONGPAOBIANXING、YANXINGJINRUN、HUAISIDENGJUNMINGXIANHAOZHUAN。QIECHU70%GANDEDASHU,SHOUSHUDANGRIXIAWUJICIRIGONGGEIGPs2CI,KESHICANLIUGANZANGDEHEFENLIEXIANGSHUMUMINGXIANZENGDUO,GANZAISHENGMINGXIANGAOYUDUIZHAOZU,BIAOMINGDUIGANXIBAOYOUCUJINZAISHENGDEZUOYONG。XIAOSHUGUANWEIJIAOGULANTIQUWU100mg/kg、200mg/kg,LIANXU3RI,DUISIYANGMIDINGTANGNIAOBINGMOXINGYOUMINGXIANJIANGXUETANGZUOYONG;BINGNENGMINGXIANGAISHANLAONIANDASHUXUETANGNAILIANGDEJIANGDI。 GPsl00mg/kgYUCHULI,DUISHUIJINDASHUZAOCHENGDEYINGJIXINGWEIKUIYANG,YOUMINGXIANBAOHUZUOYONG。GPsl00mg/kgLIANXU5RI,DUIDASHUCUSUANYOUFADEWEIKUIYANGYOUZHILIAOZUOYONG。WEI、SHIERZHICHANGKUIYANGHUANZHEMEIRIFUGPsl00-200mg,2-3GEYUE,XXIANHENEIKUIJINGJIANFAXIANHUANZHEDEKUIYANGYUHEHUOXIANZHUGAISHAN。GAOTANGGAOZHIYOUFADEDASHUGAOZHIXUEZHENGCHANGBANFAGANSUNSHANG,SHIXUEQINGBINGANSUANZHUANANMEISHANGSHENG,GPs100mg/kg、500mg/kgJIARUSILIAOZHONGFUYONG7XINGQI,KESHISHENGGAODEALTMINGXIANXIAJIANG,TISHIGPsYOUBAOGANZUOYONG。DANXIAOSHUGUANFUGPs250mg/kg、500mg/kg,SHANGXIAWUGE1CI,CIRIXIAWUFUQIANGZHUSHEKEZHIGANSUNSHANGDESILVHUATAN,DI3RICEALT,JIEGUOGPsXIANSHIWUBAOGANZUOYONG。 XIAOSHUGUANFUJIAOGULANJIANJI10g/kg、30g/kg,LIANFU7RI,DUIJUBUYINGYONGERJIABENYINQIDEERKEYANZHENGJUNYOUXIANZHUYIZHIZUOYONG,YENENGMINGXIANYIZHIFUQIANGZHUSHECUSUANSUOZHIMAOXIXUEGUANTONGTOUXINGZENGGAO。DASHUGUANFU5g/kgGONG7RIKEMINGXIANYIZHIJIAOCHACAIJIAOYINQIDEHUAIGUANJIEZHONG,DANGUANFU15g/kgGONG7RI,DUIHUAIGUANJIEZHONGSUIYOUYIZHIDANBINGWUTONGJIXUEXIANZHUXING。DUIDASHUMIANQIUROUYAZHONGYEYOUMINGXIANYIZHI,DAN5g/kgHE15g/kgYIZHIQIANGDUJIEJIN,WUJILIANGYILAIXING。SHUOMINGJIAOGULANDUISHENCHUXINGYANZHENGHEZENGZHIXINGYANZHENGJUNYOUYIZHIZUOYONG。 XIAOSHUGUANFUJIAOGULANJIANJI0.06g/ZHI、0.12g/ZHIGONG10RI,YIJIEMEIRANSEDANTIHUHUANWEIZHIBIAO,MEIYOUZHITUBIANZUOYONG,NENGSHIHUANLINXIANANYOUFADETUBIANZUOYONGMINGXIANJIANGDI。YIHUANLINXIANANYOUFAXIAOSHUWEIHE、RANSETIJIBIANJIJINGZIJIBIANWEIZHIBIAO,GPsDUIZHIJUNYOUKANGYOUBIANZUOYONG。YIADEPING、ROUHONGMEISU、DIEDANHUANA、SILIEMEISUCFENBIEZUOWEISHAMENYOUBIANJUNZHU TA97、TA98、TA100、TA102DEYOUBIANYINZI,YIHUIBIANJUNLUOSHUXIAJIANGWEIZHIBIAO,GPsZAITIWAINENGJIEKANGYISHANG4ZHONGYOUBIANYINZIDEYOUBIANZUOYONG,BINGYOUJILIANGXIAOYINGGUANXI。

【DUXING】XIAOSHUGUANFUJIAOGULANSHUITIJINGAO(GP)10,000mg/kg,72XIAOSHINEIWUSIWANG,FUQIANGZHUSHEGPDEBANSHUZHISILIANGWEI2862.5mg/kg。XIAOSHUGUANFUJIAOGULANJINGAO(HANGPsYUE20%)DEBANSHUZHISILIANGWEI4.5g/kg,BUTONGCHANDIDEJIAOGULANZONGDAIⅠHEZONGDAIⅡGEIXIAOSHUFUQIANGZHUSHEBANSHUZHISILIANGFENBIEWEI899.50-1051.32mg/kgHE1743.25-2049.11mg/kg。LINGYOUBAODAO,XIAOSHUFUQIANGZHUSHEGPsDEBANSHUZHISILIANGWEI755mg/kg,KOUFUWUDUXING。DASHUFUQIANGZHUSHEJIAOGULANCUTIWUBANSHUZHISILIANGWEI1850mg/kg,JINGKOUFUYONG10g/kgWEIJIANDUXING。MEIRIWEIFU8g/kg,LIANXU1GEYUE,YIBANQINGKUANG、TIZHONGZENGCHANG、JINSHILIANG、XUE、NIAOCHANGGUIHEBINGLIZUZHIXUEJIANCHAJUNWEIFAXIANYICHANG。

657彩票网 北京pk10 【XINGWEI】WEIKU;WEIGAN;XINGLIANG

【GUIJING】GUIFEI;PI;SHENJING

【GONGNENGZHUZHI】QINGRE;BUXU;JIEDU。ZHUTIXUFALI;XULAOSHIJING;BAIXIBAOJIANSHAOZHENG;GAOZHIXUEZHENG;BINGDUXINGGANYAN;MANXINGWEICHANGYAN;MANXINGQIGUANYAN

657彩票网 北京pk10 【YONGFAYONGLIANG】NEIFU:JIANTANG,15-30g,YANMO,3-6g;HUOPAOCHAYIN。WAIYONG:SHILIANG,DAOLANTUCA。

657彩票网 北京pk10 【ZHAILU】《ZHONGHUABENCAO》

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